| Name | PPQ-102 |
| Synonyms | PPQ-102 CS-1365 PPQ102 PPQ 102 CFTR Inhibitor CFTR INHIBITOR PPQ-102, CFTR Inhibitor |
| CAS | 931706-15-9 |
| Molecular Formula | C26H22N4O3 |
| Molar Mass | 438.48 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Melting Point | >300℃ (ethanol ) |
| Boling Point | 648.7±65.0 °C(Predicted) |
| Appearance | White crystalline solid |
| pKa | 1.00±0.40(Predicted) |
| Storage Condition | -20C |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.281 ml | 11.403 ml | 22.806 ml |
| 5 mM | 0.456 ml | 2.281 ml | 4.561 ml |
| 10 mM | 0.228 ml | 1.14 ml | 2.281 ml |
| 5 mM | 0.046 ml | 0.228 ml | 0.456 ml |
| biological activity | PPQ-102 (CFTR Inhibitor IV) is an effective CFTR inhibitor. PPQ-102 can completely suppress the current of CFTR chloride, and its IC50 value is about 90 nM. |
| target | TargetValue CFTR chloride current (Cell-free assessment) 90 nM |
| Target | Value |
| CFTR chloride current (Cell-free assay) | 90 nM |