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Parthenolide

Parthenolide

CAS: 20554-84-1;29552-41-8

Molecular Formula: C15H20O3

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Parthenolide - Names and Identifiers

Name Parthenolide
Synonyms Parthenlide
Parthenolide
4,5ξ-epoxy-6α-hydroxy-4ξH-germacra-1(10)t,11(13)-dien-12-oic acid-lactone
4Xi-germacra-1(10),11(13)-dien-12-oic acid, 4,5-epoxy-6.alpha.-hydroxy-, gamma-lactone
2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one
Oxireno(9,10)cyclodeca(1,2-B)furan-9(1ah)-one, 2,3,6,7,7A,8,10A,10B-octahydro-1A,5-dimethyl-8-methylene-
(4Z)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
(4E,7aS,10aS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
(1aR,4E,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
(1aR,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
(1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
(1aR,4Z,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
CAS 20554-84-1
29552-41-8
InChI InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11?,12-,13-,15+/m0/s1

Parthenolide - Physico-chemical Properties

Molecular FormulaC15H20O3
Molar Mass248.32
Density1.13g/cm3
Melting Point115-116ºC(lit.)
Boling Point394.095°C at 760 mmHg
Specific Rotation(α)-81.4 (c, 1.04 in CHCl3)
Flash Point166.344°C
Solubility Soluble in organic solvents such as acetone, ethyl acetate, DMSO, etc., insoluble in water.
Vapor Presure0mmHg at 25°C
AppearanceBrown yellow powder
Storage Condition2-8℃
Refractive Index1.533
MDLMFCD00134592
Physical and Chemical PropertiesSoluble in organic solvents such as acetone, ethyl acetate, DMSO, etc., insoluble in water. Tsoongiodendronodorum Chun, a plant of the genus Magnolia, comes from the genus Magnolia.

Parthenolide - Reference

Reference
Show more
1. Su Jiezhi, Zheng Liping, Zhong Junhua, Fan Pingming, Chen Zhilin. Parthenolide induces autophagy in breast cancer MCF-7 cells through ERK/MAPK pathway [J]. Chinese Pharmacist, 2019,22(07):1236-1239.

Parthenolide - Introduction

Parthenolide is a common organic compound with the chemical formula C15H12O5. The following is an introduction to the nature, use, formulation, and safety information of Parthenolide.

Nature:
Parthenolide is a white crystalline solid with a sweet taste. It has a melting point of about 228-230°C and is soluble in some organic solvents, such as ethanol, acetone and ethyl acetate.

Use:
Parthenolide is widely used in the food, beverage and pharmaceutical industries. It has a good sweetness. Compared with sucrose, its sweetness is about 300 times that of sucrose, but the calories are very low. Therefore, Parthenolide is commonly used as a low-calorie sweetener for the manufacture of low-sugar, low-calorie foods and beverages.

Preparation Method:
Parthenolide can be obtained by chemical synthesis. A common method is to chemically convert white chrysanthemum sugar (a naturally occurring substance) into Parthenolide through steps such as acid catalysis.

Safety Information:
Parthenolide is widely regarded as a safe food additive with very low toxicity to humans. In food processing, very small amounts are usually required to achieve the desired sweetening effect. However, for some people, there may be an allergy to Parthenolide or an adverse reaction. Therefore, when using Parthenolide, the appropriate dosage limits should be observed, as well as the use according to the individual constitution and the doctor's advice.

In General, Parthenolide is a safe, low-calorie, high-sweetness food additive that is widely used in the manufacture of low-sugar, low-calorie foods and beverages.
Last Update:2024-04-09 20:45:29
Parthenolide
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsMultiple SpecificationsSpot supply
Product Name: Parthenolide Visit Supplier Webpage Request for quotation
CAS: 20554-84-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
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CAS: 20554-84-1
Tel: 021-60556179
Email: 18721521379@163.com
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Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Parthenolide Request for quotation
CAS: 20554-84-1
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Nantong Reform Petro-Chemical CO., LTD.
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Product Name: Parthenolide Request for quotation
CAS: 20554-84-1
Tel: +86-13776910623
Email: r@reformchem.com­
Mobile: +86-13776910623
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Multiple SpecificationsSpot supply
Product Name: (-)-Parthenolide Request for quotation
CAS: 20554-84-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: (-)-Parthenolide Visit Supplier Webpage Request for quotation
CAS: 20554-84-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Changsha Staherb Natural Ingredients Co., Ltd.,
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Product Name: Tanacetum parthenium Parthenolide Visit Supplier Webpage Request for quotation
CAS: 20554-84-1
Tel: +86-(0)731-84213302
Email: sales@staherb.cn
Mobile: +86 13875855783 18374838656
QQ: 484702402 Click to send a QQ message
Wechat: +86 13875855783
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MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Parthenolide (Standard) Visit Supplier Webpage Request for quotation
CAS: 20554-84-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Parthenolide Visit Supplier Webpage Request for quotation
CAS: 29552-41-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Parthenolide Visit Supplier Webpage Request for quotation
CAS: 20554-84-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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