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Pazufloxacin

Pazufloxacin

CAS: 127045-41-4;166665-94-7

Molecular Formula: C16H15FN2O4

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Pazufloxacin - Names and Identifiers

Name Pazufloxacin
Synonyms T-3761
ALKALYL
Pazufloxacin
Pazufloxaxin
PAZUFLOXAXIN
Pazufloxacinmyesylate
Pazufloxaxin mesilate
(s)-yclopropyl)-9-fluoro-3-methyl-7-oxo
10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(3S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(3S)-10-(1-AMINOCYCLOPROPYL)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID
7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (R)-
(3s)-10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid C16H15FN2O4
CAS 127045-41-4
166665-94-7
EINECS 635-036-1
InChI InChI=1/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)

Pazufloxacin - Physico-chemical Properties

Molecular FormulaC16H15FN2O4
Molar Mass318.3
Density1.56
Melting Point269-271°C
Boling Point531.5±50.0 °C(Predicted)
Specific Rotation(α)D25 -88.0° (c = 0.5 in 0.05N aq NaOH)
Flash Point275.2°C
Solubility Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly,
Vapor Presure4E-12mmHg at 25°C
Appearanceneat
ColorOff-White to Pale Yellow
pKa5.05±0.40(Predicted)
Storage Condition2-8°C
Refractive Index1.692
Physical and Chemical PropertiesDensity 1.56
melting point 269-271°C
UseThis product is the key intermediate of the National Class II new drug pazufloxacin mesylate, that is, the base material, is the main part of the molecular structure, only with the salt of methane sulfonic acid to get the raw material.

Pazufloxacin - Risk and Safety

Risk CodesR20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R34 - Causes burns
R11 - Highly Flammable
Safety DescriptionS36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16 - Keep away from sources of ignition.
WGK Germany3
RTECSUU8815300
ToxicityLD50 i.v. in male mice: >500 mg/kg (Todo)

Pazufloxacin - Reference

Reference
Show more
1. [IF=7.514] Bolong Fang et al."Glucose oxidase-induced colorimetric immunoassay for qualitative detection of danofloxacin based on iron (Ⅱ) chelation reaction with phenanthroline."Food Chem. 2020 Oct;328:127099
2. [IF=6.057] Song Hu et al."Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food."Talanta. 2020 Nov;219:121245

Pazufloxacin - Preparation solution concentration reference

 1mg5mg10mg
1 mM3.142 ml15.708 ml31.417 ml
5 mM0.628 ml3.142 ml6.283 ml
10 mM0.314 ml1.571 ml3.142 ml
5 mM0.063 ml0.314 ml0.628 ml
Last Update:2024-01-02 23:10:35
Pazufloxacin
Supplier List
Hubei Rhema Reference Materials Technology Co., Ltd.
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Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: (R)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Request for quotation
CAS: 166665-94-7
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Pazufloxacin Request for quotation
CAS: 127045-41-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Pazufloxacin Visit Supplier Webpage Request for quotation
CAS: 127045-41-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Pazufloxacin Visit Supplier Webpage Request for quotation
CAS: 127045-41-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: T3761 Visit Supplier Webpage Request for quotation
CAS: 127045-41-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Pazufloxacin Visit Supplier Webpage Request for quotation
CAS: 127045-41-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Pazufloxacin Visit Supplier Webpage Request for quotation
CAS: 127045-41-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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