Peimisine
Peimisine
CAS: 19773-24-1
Molecular Formula: C27H41NO3
Peimisine - Names and Identifiers
Peimisine - Physico-chemical Properties
| Molecular Formula | C27H41NO3 |
| Molar Mass | 427.62 |
| Density | 1.17 |
| Melting Point | 270℃ |
| Boling Point | 573.0±50.0 °C(Predicted) |
| Specific Rotation(α) | (c, 1 in CHCl3)-33.2;(c, 0.58 in EtOH)-44.6 |
| Solubility | Soluble in chloroform, ether, methanol |
| Appearance | Colorless crystalline powder |
| pKa | 14.89±0.70(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| MDL | MFCD30207851 |
| Physical and Chemical Properties | White crystalline powder, soluble in chloroform, ether, methanol, derived from Fritillaria fritillary. |
Peimisine - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29389090 |
Peimisine - Reference
| Reference Show more | 1. Pan Feng, Houkai, Dong pinli, et al. Simultaneous determination of three kinds of alkaloids in Fritillaria tabuensis by HPLC-ELSD method [J]. Journal of Nuclear agronomy: 2014 28(010):1854-1859. 2. Cui Yanru, Liu Haiyun, Qu Fei. Effect of beimuxin on the expression of MUC5AC and EGFR in LPS-induced mucus hypersecretion mice [J]. Pharmacology and Clinic of Traditional Chinese Medicine, 2015, 25 (03):17-21. 3. Cui Yanru, Liu Haiyun, Qu Fei. Protective effect of Fritillaria on endotoxin-induced acute lung injury in mice [J]. Shi Zhen, National Medicine, 2014,25(09):2118-2120. 4. Wang Yuanbiao, Liu Zhengqiong, et al. Screening and identification of alkaloid-producing endophytic fungi from Fritillaria Gansu and determination of their antibacterial activities. China Agricultural Science Bulletin 2012. 5. Han Hongping, Zheng hongma Tianyi et al. Molecular imprinting-chemiluminescence sensor for the determination of Fritillaria type B [J]. Chemical reagent 2016 038(011):1081-1085. 6. Chen que, Wang Yuanbiao, Liu Zhengqiong, etc. Screening of alkaloid-producing endophytic fungi from Fritillaria Aurea and determination of alkaloid antibacterial activity [J]. Chinese Journal of antibiotics, 2012. 7. Yu Tian, Qi Xin Jie, Sun You Ling, etc. Analysis of the origin of Fritillaria Thunbergii and its content after ex-situ introduction [J]. Journal of Chengdu University (Natural Science Edition), 2018, 37(04):36-38 49. 8. Cheng Bin, Zhou Aizhen, Peng Xin, Wang Xinlei, Wang Juan. Establishment of UPLC-Q-TOF-MS/MS fingerprint of Fritillaria Thunbergii and analysis of anti-inflammatory markers [J]. China Pharmacy, 2020,31(17): 2149-2135. 9. Pan, Feng, et al. "Fusarium redolens 6WBY3, an endophytic fungus isolated from Fritillaria unibracteata var. wabuensis, produces peimisine and imperialine-3β-d-glucoside." Fitoterapia 103 (2015): 213-221.https://doi.org/10.1016/j.fitote.2015.04.006 10. Feng Pan, Kai Hou, Feng Gao, Bo Hu, Que Chen, Wei Wu Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis, Phytomedicine, Volume 21, Issues 8-9, 2014, Pages 1104-1109, ISSN 0944-7113, ht 11. [IF=5.34] Feng Pan et al."Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis."Phytomedicine. 2014 Jul;21:1104 12. [IF=2.882] By Feng Pan et al."Fusarium redolens 6WBY3, an endophytic fungus isolated from Fritillaria unibracteata var. wabuensis, produces peimisine and imperialine-3β-d-glucoside."Fitoterapia. 2015 Jun;103:213 13. [IF=4.411] Simona S. Ghanem et al."Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity."Molecules. 2021 Jan;26(12):3736 14. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 15. [IF=4.769] Ting Zheng et al."Delineating the dynamic metabolic profile of Qi-Yu-San-Long decoction in rat urine using UPLC-QTOF-MSE coupled with a post-targeted screening strategy."Journal of Pharmaceutical Analysis. 2022 May ;: |
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