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Pentids

Benzylpenicillin potassium

CAS: 113-98-4

Molecular Formula: C16H17KN2O4S

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Pentids - Names and Identifiers

Name Benzylpenicillin potassium
Synonyms R-Pen
Pen-G
Forpen
Pentid
Falapen
tabilin
Tabilin
Pentids
Hylenta
Monopen
Hyasorb
Orpeneed
Liquapen
Cosmopen
M-cillin
Novopen-G
Cristapen
Dixocillin
Eskacillin
Truxcillin
Hipercilina
Sugracillin
4-Thia-1-azabicyclo
PENICILLIN G K-SALT
Unilab Penicillin G
PENICILLIN G POTASSIUM
Penicillin G potassium
Benzylpenicillin potassium
potassium benzylpenicillin
PENICILLIN G POTASSIUM SALT
Potassium benzylpenicillinate
Benzylpenicillinic acid potassium salt
Monopotassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1 -azabicyclo
potassium 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
potassium [2S-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
potassium [2s-(2alpha,5alpha,6beta)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, [2S-(2alpha,5alpha,6beta)]-, monopotassium salt
CAS 113-98-4
EINECS 204-038-0
InChI InChI=1/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/t11-,12+,14-;/m1./s1
InChIKey IYNDLOXRXUOGIU-LQDWTQKMSA-M

Pentids - Physico-chemical Properties

Molecular FormulaC16H17KN2O4S
Molar Mass372.48
Melting Point214-217 C
Specific Rotation(α)D22 +285° (c = 0.748 in water)
Water SolubilitySoluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
Solubility H2O: 100mg/mL
AppearancePowder
ColorNeedles from butanol (aq)
Merck14,7094
BRN3832841
PHpH (10g/L, 25℃) : 5.0~7.5
Storage ConditionSealed in dry,Store in freezer, under -20°C
StabilityHygroscopic
Refractive Index294 ° (C=1, H2O)
MDLMFCD00036193
UseBelongs to high efficiency and low toxicity antibiotics

Pentids - Risk and Safety

Risk CodesR42/43 - May cause sensitization by inhalation and skin contact.
R34 - Causes burns
R11 - Highly Flammable
Safety DescriptionS36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16 - Keep away from sources of ignition.
S60 - This material and its container must be disposed of as hazardous waste.
S37 - Wear suitable gloves.
S24 - Avoid contact with skin.
S22 - Do not breathe dust.
WGK Germany2
RTECSXH9700000
FLUKA BRAND F CODES10-23
TSCAYes
HS Code29411000
ToxicityLD50 oral in rabbit: 5848mg/kg

Pentids - Upstream Downstream Industry

Raw MaterialsPhenylacetic acid
Phenylacetic acid
n-Butyl acetate
1-Butanol
Dextrose Anhydrate
Potassium carbonate
Potassium carbonate
Ethyl Alcohol
1-Butanol
Downstream Products6-Aminopenicillanic acid
procaine penicillin

Pentids - Standard

Authoritative Data Verified Data

(25,5R,6R)-3, 3-dimethyl-6-(2-phenylacetamido)-7-oxo-4-thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid potassium salt. Calculated as dry product, including C16H17KN204S shall not be less than 96.0%.

Last Update:2024-01-02 23:10:35

Pentids - Trait

Authoritative Data Verified Data
  • This product is a white crystalline powder; Odorless or slightly specific odor; Hygroscopicity; Rapid failure when exposed to acid, alkali or oxidant, and easy failure when placed in aqueous solution at room temperature.
  • This product is easily soluble in water, slightly soluble in ethanol, insoluble in fatty oil or liquid paraffin.
Last Update:2022-01-01 13:33:02

Pentids - Differential diagnosis

Authoritative Data Verified Data
  1. in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.
  2. The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 223).
  3. This product shows the reaction of potassium salt identification (1) (General rule 0301).
Last Update:2022-01-01 13:33:02

Pentids - Exam

Authoritative Data Verified Data

absorbance

take this product, precision weighing, adding water to dissolve and quantitatively dilute the solution containing 0401 mg per lml, according to UV-visible spectrophotometry (general) determination, in the wavelength of 280nm and 325nm, the absorbance should not be greater than 0.10; In the wavelength of 264nm, there is maximum absorption, absorbance should be 0.80~0.88.


visible foreign body

take 5 parts of this product, each 0.625g, plus particle inspection water dissolution, inspection according to law (General 0904), should comply with the provisions. (For aseptic dispensing)


insoluble particles

Take 3 parts of this product, and make a solution containing 50mg per lml of water for particle inspection, and check it according to law (General rule 0903). In each lg sample, particles containing 10um and more than 10um shall not exceed 6000 particles, and particles containing 25um and more than 25um shall not exceed 600 particles. (For aseptic dispensing)


crystallinity, pH, clarity and color of the solution, related substances, penicillin polymer, loss on drying, bacterial endotoxin (for injection) and sterility (for aseptic dispensing)

According to the method under the item of penicillin sodium inspection, should comply with the provisions.

Last Update:2022-01-01 13:33:03

Pentids - Content determination

Authoritative Data Verified Data

take this product, according to the method under the item of penicillin sodium, according to the external standard method to calculate the peak area, the result is multiplied by 1.1136, that is, the content of C16H17KN2O4S in the sample.

Last Update:2022-01-01 13:33:03

Pentids - Category

Authoritative Data Verified Data

B-lactam antibiotics, penicillins.

Last Update:2022-01-01 13:33:04

Pentids - Storage

Authoritative Data Verified Data

sealed and stored in a cool, dark and dry place.

Last Update:2022-01-01 13:33:04

Pentids - Penicillin potassium for injection

Authoritative Data Verified Data

This product is a crystalline sterile powder of penicillin potassium. The content of Cl6H17KN204S shall not be less than 96.0% based on the dry product; The content of C16H17KN204S shall be 95.0% ~ 115.0% of the label amount based on the average loading.


trait

This product is a white crystalline powder.


Post

take this product, according to penicillin potassium under the identification test, showed the same results.


examination

  • the clarity and color of the solution should be checked according to the method under the item of penicillin sodium for injection, and should comply with the regulations.
  • the content under the item of difference in loading amount of penicillin polymer shall be accurately weighed and appropriately measured according to the method of penicillin sodium and calculated by the external standard method based on penicillin peak volume, the amount of penicillin polymer should not exceed 0.10% of the labeled amount.
  • weight loss on drying this product, drying at 105°C, weight loss shall not exceed 1.0% (General rule 0831).
  • insoluble particles this product is taken, and the labeled amount is added to the particle inspection water to make a solution containing 50mg per 1 ml, which is inspected according to law (General rule 0903), and the labeled amount is l. The conversion below Og is per l. In the Og sample, the particles containing l0um and 10um or more shall not exceed 6000 particles, and the particles containing 25um and 25um or more shall not exceed 600 particles.
  • the pH value, related substances, bacterial endotoxin and sterility shall be checked according to the method under the item of penicillin sodium, and shall be in accordance with the regulations.
  • others should comply with the relevant provisions under injection (General 0102).

Content determination

The content under the item of loading amount difference was accurately weighed and an appropriate amount was measured according to the method of penicillin potassium. Each 1 mg of C16H17KN204S is equivalent to 1598 penicillin units.


category

with penicillin potassium.


specification

According to C16H17KN204S (1)0.l25g (200,000 units)(2)0.25g (400,000 units) (3)0.5g (800,000 units) (4)0.625g(1 million units)


storage

sealed and stored in a cool, dark and dry place.

Last Update:2022-01-01 13:33:05
Pentids
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 113-98-4
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Penicillin G potassium salt Visit Supplier Webpage Request for quotation
CAS: 113-98-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
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Product Name: Benzylpenicillin potassium Request for quotation
CAS: 113-98-4
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Benzylpenicillin potassium Request for quotation
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685 Click to send a QQ message
Wechat: chemical6666
Nantong Reform Petro-Chemical CO., LTD.
Product Name: Benzylpenicillin potassium Request for quotation
CAS: 113-98-4
Tel: +86-13776910623
Email: r@reformchem.com­
Mobile: +86-13776910623
QQ: 3785839865 Click to send a QQ messageSend QQ message
Wechat: chemical6666 
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Penicillin G potassium Request for quotation
CAS: 113-98-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Penicillin G (potassium) Visit Supplier Webpage Request for quotation
CAS: 113-98-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Penicillin G potassium (Standard) Visit Supplier Webpage Request for quotation
CAS: 113-98-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Benzylpenicillin Potassium Visit Supplier Webpage Request for quotation
CAS: 113-98-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Benzylpenicillin potassium Request for quotation
CAS: 113-98-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
     info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Penicillin G Potassium salt Visit Supplier Webpage Request for quotation
CAS: 113-98-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Pentids
氧化汞(II)红
Acetone
2,7-Pyrendicarboxaldehyd
Raw Materials for Pentids
1-Butanol
Ethyl Alcohol
1-Butanol
Downstream Products for Pentids
6-Aminopenicillanic acid
procaine penicillin
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