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Pinoresinol

Pinoresinol

CAS: 487-36-5

Molecular Formula: C20H22O6

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Pinoresinol - Names and Identifiers

Name Pinoresinol
Synonyms Pinoresinol
(+)-PINORESINOL
(1β,5β)-2β,6β-Bis(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
(3R,3aβ,6aβ)-3β,6β-Bis(3-methoxy-4-hydroxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol)
(-)-4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol)
(1S)-1β,4β-Bis(4-hydroxy-3-methoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan
(3aS,6aS)-3a,4,6,6a-Tetrahydro-3β,6β-bis(4-hydroxy-3-methoxyphenyl)-1H,3H-furo[3,4-c]furan
2-Methoxy-4-[(1R)-4α-(3-methoxy-4-hydroxyphenyl)-3aα,4,6,6aα-tetrahydro-1H,3H-furo[3,4-c]furan-1α-yl]phenol
CAS 487-36-5

Pinoresinol - Physico-chemical Properties

Molecular FormulaC20H22O6
Molar Mass358.39
Density1.385 g/cm3
Melting Point112 °C
Boling Point556.5±50.0 °C(Predicted)
Specific Rotation(α)+84.4 (Me2CO)
Solubility Soluble in methanol, ether, slightly soluble in water
AppearanceSolid
Colorwhite to tan
pKa9.54±0.35(Predicted)
Storage ConditionSealed in dry,Room Temperature
In vitro study Pinoresinol facilitated death-inducing signaling complex formation to trigger a caspase-8-dependent apoptotic cascade activation in TRAIL-resistant glioblastoma cells.

Pinoresinol - Risk and Safety

WGK Germany3

Pinoresinol - Reference

Reference
Show more
1. He, Mingzhen, et al. "Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv."
2. Chen, Yazhen, et al. "Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame." Food and Chemical Toxicology 139 (2020): 111239.https://doi.org/10.1016/j.fct.2020.111239
3. [IF=6.023] Yazhen Chen et al."Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame."Food Chem Toxicol. 2020 May;139:111239
4. [IF=3.205] Jia Jia et al."Screening of anti-complement active ingredients from Eucommia ulmoides Oliv. branches and their metabolism in vivo based on UHPLC-Q-TOF/MS/MS."J Chromatogr B. 2019 Aug;1124:26

Pinoresinol - Reference Information

Introduction pinoresin is a trace element, which mainly exists in the natural resin of plant pine.
Application people use modern technology to purify the resin, after processing can be obtained light yellow powder material, can be used for drug production, can also be used for industrial processing.
biological activity Pinoresinol is a plant-derived lignin used for defense in Trichinella spp. Pinoresinol greatly sensitizes cancer cells to TNF-related apoptosis-inducing ligand TRAIL-induced apoptosis.
Last Update:2024-04-09 21:54:55
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View History
Pinoresinol
17577-28-5
Acid Black BA
HSDB 401
pbb 80
Anglosperse Blue SBGL
4-(METHYLTHIO)BENZENETHIOL
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