Quinestrol
Quinestrol
CAS: 152-43-2
Molecular Formula: C25H32O2
Quinestrol - Names and Identifiers
| Name | Quinestrol |
| Synonyms | eston eecpe Quinestrol 17-alpha-ethinylestradiol3-cyclopentylether 17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether (17beta)-3-(cyclopentyloxy)-17-ethynylestra-1,3,5(10)-trien-17-ol 3-cyclopentyloxy-17-alpha-ethynyloestra-1,3,5(10)-trien-17-beta-ol 3-(cyclopentyloxy)-(17-alpha)-19-norpregna-5(10)-trien-20-yn-17-ol 5(10)-trien-20-yn-17-ol,3-(cyclopentyloxy)-19-nor-17-alpha-pregna-3 3-(cyclopentyloxy)-19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yn-17-ol 17ALPHA-ETHYLNYL-1,3,5[10]ESTRATRIENE-3,17BETA-DIOL 3-CYCLOPENTYL ETHER |
| CAS | 152-43-2 |
| EINECS | 205-803-1 |
| InChI | InChI=1/C25H32O2/c1-3-25(26)15-13-23-22-10-8-17-16-19(27-18-6-4-5-7-18)9-11-20(17)21(22)12-14-24(23,25)2/h1,9,11,16,18,21-23,26H,4-8,10,12-15H2,2H3/t21-,22-,23+,24+,25+/m1/s1 |
Quinestrol - Physico-chemical Properties
| Molecular Formula | C25H32O2 |
| Molar Mass | 364.52 |
| Density | 1.0693 (rough estimate) |
| Melting Point | 107-108° |
| Boling Point | 435.69°C (rough estimate) |
| Specific Rotation(α) | D25 +5° (c = 0.5 in dioxane) |
| Flash Point | 218.8°C |
| Solubility | Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 6.43E-11mmHg at 25°C |
| Appearance | Crystal |
| Color | White to Off-White |
| Merck | 14,8055 |
| pKa | 13.10±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4480 (estimate) |
| Use | Used as an estrogen |
Quinestrol - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R45 - May cause cancer R61 - May cause harm to the unborn child R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R46 - May cause heritable genetic damage |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
| RTECS | RC8948000 |
Quinestrol - Standard
Authoritative Data Verified Data
This product is 3-cyclopentyloxy-19-nor-17a-pregnan-1, 3,5 (10 )-Tris -20-alkyn-17-alcohol. Based on the dry product, the content of C25H3202 should be 97.5% ~ 102.5%.
Last Update：2024-01-02 23:10:35
Quinestrol - Trait
Authoritative Data Verified Data
- This product is white or off-white crystalline or crystalline powder.
- This product is dissolved in ethanol, acetone, ethyl acetate or chloroform, and is almost insoluble in water.
melting point
The melting point of this product (General 0612) is 106~112°C.
specific rotation
take this product, precision weighing, plus dioxane dissolution and quantitative dilution of about 10 mg per lml solution, according to the law (General 0621), the specific rotation is 0 ° to 50 °.
Last Update：2022-01-01 13:37:36
Quinestrol - Differential diagnosis
Authoritative Data Verified Data
- take about 2mg of this product, add 2ml of sulfuric acid to dissolve, the solution is orange red, under the UV lamp to observe yellow green fluorescence; Add 2ml of water, resulting in red precipitate.
- in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 1163).
Last Update：2022-01-01 13:37:37
Quinestrol - Exam
Authoritative Data Verified Data
Related substances
take this product, add anhydrous ethanol to dissolve and dilute to make a solution containing about 4mg per lml as a test solution; Take lml for precision measurement and put it in a 100ml measuring flask, as a control solution, it was diluted to scale with absolute ethanol and shaken. According to the chromatographic conditions under the content determination item, 20 u1 of the test solution and the control solution are respectively injected into the liquid chromatograph, and the chromatogram is recorded to 2 times of the retention time of the main component peak. If there are impurity peaks in the chromatogram of the test solution, the sum of each impurity peak area shall not be more than 3 times (3.0%) of the main peak area of the control solution.
loss on drying
take this product, dry to constant weight at 80°C, weight loss shall not exceed 1.0% (General rule 0831).
Last Update：2022-01-01 13:37:37
Quinestrol - Content determination
Authoritative Data Verified Data
measured by high performance liquid chromatography (General 0512).
chromatographic conditions and system suitability test
silica gel bonded with eighteen alkyl silane was used as a filler; Methanol-water (90:10) was used as a mobile phase; The detection wavelength was 279mn. Take the appropriate amount of ethinyl estradiol and ethinyl estradiol respectively, add absolute ethanol to dissolve and dilute to make each containing 0.lmg mixed solution, take 20m1 injection liquid chromatograph, the number of theoretical plate is not less than 2000 according to the peak of ethinyl estradiol, and the separation degree between ethinyl estradiol peak and ethinyl estradiol peak should be greater than 12.
assay
take an appropriate amount of this product, weigh it accurately, add anhydrous ethanol to dissolve and quantitatively dilute to make a solution containing about 0.4mg per lml, as a test solution, the chromatogram was recorded by injection of 20u1 into human liquid chromatograph, and an appropriate amount of reference substance of ethinyl estradiol was taken for determination by the same method. According to the external standard method to calculate the peak area, that is.
Last Update：2022-01-01 13:37:38
Quinestrol - Category
Authoritative Data Verified Data
estrogen drugs.
Last Update：2022-01-01 13:37:38
Quinestrol - Storage
Authoritative Data Verified Data
sealed storage.
Last Update：2022-01-01 13:37:38
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Product Name: Quinestrol Visit Supplier Webpage Request for quotationCAS: 152-43-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
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Product Name: Quinestrol Request for quotationCAS: 152-43-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Quinestrol Visit Supplier Webpage Request for quotationCAS: 152-43-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: W-3566 Visit Supplier Webpage Request for quotationCAS: 152-43-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Quinestrol Visit Supplier Webpage Request for quotationCAS: 152-43-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
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Product Name: Quinestrol Visit Supplier Webpage Request for quotationCAS: 152-43-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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