Risperidone

Risperidone - Names and Identifiers

Name	risperidone
Synonyms	Rispadal Risperidal Risoeridone risperidone Resperidone Risperdal OD Risperidone intermediates 3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)- 4-[2-[4-(6-Fluorobenzo[d]isoxazol-3-yl)-1-piperidyl]ethyl]-3-methyl-2,6-diazabicyclo[4.4.0]deca-1,3-dien-5-one 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one 3-[2-[4-(6-Fluoro-1,2-benzoisoxazole-3-yl)piperidino]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one 3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one 3-[2-4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one, R-64766, Belivon, Risperdal
CAS	106266-06-2
EINECS	600-733-1
InChI	InChI=1/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

Risperidone - Physico-chemical Properties

Molecular Formula	C23H27FN4O2
Molar Mass	410.48
Density	1.38±0.1 g/cm3(Predicted)
Melting Point	170°C
Boling Point	572.4±60.0 °C(Predicted)
Flash Point	9℃
Water Solubility	44.74mg/L(25 ºC)
Solubility	Soluble in DMSO (10 mM), ethanol (10 mM), chloroform, and methanol. Insoluble in water.
Vapor Presure	4.14E-13mmHg at 25°C
Appearance	White to white-like powder
Color	white to off-white
Merck	14,8233
pKa	pKa 8.3 (Uncertain)
Storage Condition	2-8°C
Refractive Index	1.676
MDL	MFCD00274576
Physical and Chemical Properties	Crystallized from dimethylformamide-isopropanol, melting point 170.0 °c. Acute toxicity LD50 male and female mice, male and female rats, male and female dogs (mg/kg):29.7,26.9,34.3,35.4,14.1,18.3 intravenous injection; 82.1,63.1,113,56.6,18.3,18.3 Po.
Use	Antipsychotics

Risperidone - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable
Safety Description	S28 - After contact with skin, wash immediately with plenty of soap-suds. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition.
UN IDs	3249
WGK Germany	3
RTECS	UV1164800
HS Code	29333990
Hazard Class	6.1(a)
Packing Group	II
Toxicity	LD50 in male, female mice, rats, dogs (mg/kg): 29.7, 26.9, 34.3, 35.4, 14.1, 18.3 i.v.; 82.1, 63.1, 113, 56.6, 18.3, 18.3 orally (Janssen, 1988)

Risperidone - Reference

Reference

1. [IF=6.057] Wen-Hua Ji et al."A water-compatible magnetic molecularly imprinted polymer for the selective extraction of risperidone and 9-hydroxyrisperidone from human urine."Talanta. 2018 May;181:392
2. [IF=3.119] Jinrui Zhang et al."In silico study on identification of novel MALT1 allosteric inhibitors."Rsc Adv. 2019 Nov;9(67):39338-39347

Risperidone - Introduction

Risperidone is an atypical sedative used in the treatment of schizophrenia.

Last Update：2022-10-16 17:11:48

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View History

Risperidone
4-Hydroxy-alpha-aminoacetophenone

Risperidone

risperidone

CAS: 106266-06-2

Molecular Formula: C23H27FN4O2

Risperidone - Names and Identifiers

Risperidone - Physico-chemical Properties

Risperidone - Risk and Safety

Risperidone - Reference

Risperidone - Introduction

Supplier List

Risperidone Request for Quotation

risperidone

CAS: 106266-06-2

Molecular Formula: C23H27FN4O2

Risperidone - Names and Identifiers

Risperidone - Physico-chemical Properties

Risperidone - Risk and Safety

Risperidone - Reference

Risperidone - Introduction

Supplier List

Risperidone