Rubiadin
Rubiadin
CAS: 117-02-2
Molecular Formula: C15H10O4
Rubiadin - Names and Identifiers
Rubiadin - Physico-chemical Properties
| Molecular Formula | C15H10O4 |
| Molar Mass | 254.24 |
| Density | 1.476 |
| Melting Point | 290℃ |
| Boling Point | 527.1±30.0 °C(Predicted) |
| Solubility | Soluble in acetone, DMSO, methanol |
| Appearance | Yellow or red powder |
| BRN | 1885558 |
| pKa | 7.22±0.20(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD02752095 |
| Physical and Chemical Properties | From Morinda officinalis |
Rubiadin - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
| HS Code | 29146990 |
Rubiadin - Reference
| Reference Show more | 1. Feng Hongyao, Zeng Lingjie, Huang Han, Mo Yuncai, Zhang Xiu-qing, Liang Zhang, Liao Su-Xi, Guo Yu-Mei. Distribution and accumulation of methyl isoalizarin, Crystal lanoside and polysaccharide in root, stem and leaf of Morinda officinalis how [J]. West China Pharmaceutical Journal, 2017,32(02):208-210. 2. Wu Ling-feng, Wen Haitao, Liang Xiang, Xie Hua-song, Luo Bao-ping. Quality Evaluation of anthraquinones fingerprint of Morinda officinalis how wild herbs and cultivars [J]. Electronic Journal of Clinical medical literature, 2016,3(32):6327, 6401. 3. [IF = 3.935] Dandan Zhang et al."Discovering the main." J Pharmaceut Biomed. 2022 Jan;207:114422 |
Rubiadin - Reference Information
| Overview | the content of anthraquinones in Morinda officinalis is relatively high, it is widely distributed in many plants, such as Rubiaceae, bitter wood and so on. It is rich in resources, and has anti-tuberculosis, anti-fungal, anti-cancer activity, anti-osteoporosis and other effects. figure: Morinda officinalis |
| pharmacological applications | methylisoalizarin is widely distributed in many plants, such as alizarin, it is rich in resources and has no estrogen-like effect as a bone resorption inhibitor, so it is often used in bone destructive diseases such as osteoporosis, rheumatoid arthritis, periodontal disease and cancer bone metastasis. |
| determination | method: the chromatographic column was Column ODS-BPC18, the mobile phase was phosphoric acid, and the main temperature was 30 ℃, the flow rate was 1.0 and the detection wavelength was 227nm. Results: the calibration curve was linear in the range of 4.24-42.4ug/ml. The average recovery was 99.8%,. Conclusion The method is simple, accurate, accurate, reliable and reproducible for the determination of the content of methyl isoalizarin in Morinda officinalis. |
| references | [1] Chen Ali, Yang Yongxia, Wang Shumei, etc. Determination of methylisoalizarin in Morinda officinalis how by HPLC [J]. Chinese Journal of Modern Pharmaceutical Applications, 2013, 7(21):223-224. [2] Bao Leilei, Qin Luping, bianjun, et al. Effect of Morinda officinalis on Osteoclastic bone resorption [J]. Chinese PLA Journal of Pharmacy, 2009, 25(6):505-509. |
| Chemical properties | from Morinda officinalis |
| Use | for content determination/identification/pharmacological experiments |
| Color index | 75350 |
Last Update：2024-04-09 21:04:16
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