SACLOFEN
SACLOFEN
CAS: 125464-42-8
Molecular Formula: C9H12ClNO3S
SACLOFEN - Names and Identifiers
| Name | SACLOFEN |
| Synonyms | SACLOFEN SACLOFEN SELECTIVE GABA(B) REC 3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID 3-AMino-2-(4-chlorophenyl)propane-1-sulfonic acid (RS)-3-amino-2-(4-chlorophenyl)propylsulfonic acid β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid (RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID BETA-(AMINOMETHYL)-4-CHLORO-BENZENEETHANESULPHONIC ACID |
| CAS | 125464-42-8 |
| InChI | InChI=1/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14) |
| InChIKey | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
SACLOFEN - Physico-chemical Properties
| Molecular Formula | C9H12ClNO3S |
| Molar Mass | 249.71 |
| Density | 1.437±0.06 g/cm3(Predicted) |
| Melting Point | 310-315℃ (decomposition) |
| Solubility | 0.1 M NaOH: 20mg/mL |
| Appearance | solid |
| Color | white |
| pKa | 1.15±0.50(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6 |
| Physical and Chemical Properties | Solubility: 0.1 M NaOH: 20 mg/mL WGK Germany:3 |
SACLOFEN - Risk and Safety
| WGK Germany | 3 |
SACLOFEN - Introduction
3-Amino -2-(4-chlorophenyl)-propanesulfonic acid (abbreviated as ACPA) is an organic compound. It has a chemical formula of C9H12ClNO3S and a molecular weight of about 239.71g/mol.
ACPA is a solid, usually white crystalline powder. It is stable at room temperature, but may decompose at high temperatures or under the action of strong acids. ACPA has a high solubility in water and a relatively low solubility in organic solvents.
ACPA has pharmaceutical activity and is widely used as a pharmaceutical intermediate. It is a non-guanine PPARγ agonist and is used in the field of diabetes treatment. In addition, ACPA can also be used to synthesize other drugs, such as anti-tumor drugs and anti-inflammatory drugs.
The preparation of ACPA is usually achieved by chemical synthesis. A common synthetic method is to react 4-chloroacetophenone with sulfuric acid and an oxidizing agent to produce 3-amino -2-(4-chlorophenyl)-propenone, which is then reacted with threesulfonic acid to form ACPA.
Some safety information needs to be paid attention to when using and handling ACPA. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as safety glasses, gloves and respiratory protection equipment. At the same time, it should be used in a well-ventilated laboratory environment and avoid contact with strong acids and strong oxidants to avoid dangerous reactions.
In summary, 3-amino -2-(4-chlorophenyl)-propanesulfonic acid is an organic compound with pharmaceutical activity and has important applications in the fields of drug synthesis and diabetes treatment. However, safety precautions should be paid attention to when using and handling.
ACPA is a solid, usually white crystalline powder. It is stable at room temperature, but may decompose at high temperatures or under the action of strong acids. ACPA has a high solubility in water and a relatively low solubility in organic solvents.
ACPA has pharmaceutical activity and is widely used as a pharmaceutical intermediate. It is a non-guanine PPARγ agonist and is used in the field of diabetes treatment. In addition, ACPA can also be used to synthesize other drugs, such as anti-tumor drugs and anti-inflammatory drugs.
The preparation of ACPA is usually achieved by chemical synthesis. A common synthetic method is to react 4-chloroacetophenone with sulfuric acid and an oxidizing agent to produce 3-amino -2-(4-chlorophenyl)-propenone, which is then reacted with threesulfonic acid to form ACPA.
Some safety information needs to be paid attention to when using and handling ACPA. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as safety glasses, gloves and respiratory protection equipment. At the same time, it should be used in a well-ventilated laboratory environment and avoid contact with strong acids and strong oxidants to avoid dangerous reactions.
In summary, 3-amino -2-(4-chlorophenyl)-propanesulfonic acid is an organic compound with pharmaceutical activity and has important applications in the fields of drug synthesis and diabetes treatment. However, safety precautions should be paid attention to when using and handling.
Last Update：2024-04-09 21:11:58
Supplier List
Spot supply
Product Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid Request for quotationCAS: 125464-42-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Saclofen Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: SACLOFEN Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: SACLOFEN Visit Supplier Webpage Request for quotation
CAS: 125464-42-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 125464-42-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid Request for quotationCAS: 125464-42-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Saclofen Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: SACLOFEN Visit Supplier Webpage Request for quotationCAS: 125464-42-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: SACLOFEN Visit Supplier Webpage Request for quotation
CAS: 125464-42-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 125464-42-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History