| Molecular Formula | C24H20ClN3O |
| Molar Mass | 401.89 |
| Melting Point | 202-205°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | -20°C, Inert atmosphere |
| In vivo study | Specific inhibition of protozoan CYP51 can potentially provide treatment for human trypanosomiases. |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.488 ml | 12.441 ml | 24.883 ml |
| 5 mM | 0.498 ml | 2.488 ml | 4.977 ml |
| 10 mM | 0.249 ml | 1.244 ml | 2.488 ml |
| 5 mM | 0.05 ml | 0.249 ml | 0.498 ml |
| biological activity | NVP-VID-400 (SDZ285428) is an inhibitor of CYP51. The I/E2a(5 min) values of NVP-VID-400 (SDZ285428) inhibition T. cruzi and T. brucei were both <1 and I/E2(60 min) values were 9 and 35, respectively. |
| target | TargetValue CYP51 () |
| Target | Value |
| in vivo study | Specific inhibition of protozoan CYP51 can potentially provide treatment for human trypanosomiases. |