SF1670
SF1670
CAS: 345630-40-2
Molecular Formula: C19H17NO3
SF1670 - Names and Identifiers
SF1670 - Physico-chemical Properties
| Molecular Formula | C19H17NO3 |
| Molar Mass | 307.34 |
| Density | 1.271±0.06 g/cm3(Predicted) |
| Boling Point | 554.1±29.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| Appearance | Red-violet solid |
| Color | , light pink to red to very dark purple |
| pKa | 14.31±0.20(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | SF1670 showed potent cytotoxicity in HBEC,PC-3,H1299 cells, with IC50 of 5 μm, 10 μm, 44 μm, respectively. SF1670 stimulates the process of angiogenesis in a mouse aortic ring artificial basement membrane angiogenesis model. SF1670 increases chemoattractant-induced PtdIns(3,4,5)P3 signaling in neutrophils and enhances neutrophil function. |
| In vivo study | In neutropenic peritonitis and bacterial Pneumonia mice, SF1670 pretreatment (500 nM, I. V.) increased Bactericidal Capacity and decreased Pneumonia of Mortality Rate associated with neutropenia. |
SF1670 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
SF1670 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.254 ml | 16.268 ml | 32.537 ml |
| 5 mM | 0.651 ml | 3.254 ml | 6.507 ml |
| 10 mM | 0.325 ml | 1.627 ml | 3.254 ml |
| 5 mM | 0.065 ml | 0.325 ml | 0.651 ml |
Last Update：2024-01-02 23:10:35
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