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THZ2

THZ2

CAS: 1604810-84-5

Molecular Formula: C31H28ClN7O2

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THZ2 - Names and Identifiers

Name THZ2
Synonyms THZ2
THZ 2
THZ-2
CS-1182
CDK7-IN-1
THZ2,CDK7-IN-1
(E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(4-(dimethylamino)but-2-enamido)benzamide
Benzamide, N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-3-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-
CAS 1604810-84-5

THZ2 - Physico-chemical Properties

Molecular FormulaC31H28ClN7O2
Molar Mass566.05
Density1.379±0.06 g/cm3(Predicted)
Solubility DMSO: ≥ 39 mg/mL
pKa13.06±0.70(Predicted)
Storage Condition-20℃

THZ2 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.767 ml8.833 ml17.666 ml
5 mM0.353 ml1.767 ml3.533 ml
10 mM0.177 ml0.883 ml1.767 ml
5 mM0.035 ml0.177 ml0.353 ml
Last Update:2024-01-02 23:10:35

THZ2 - Reference Information

biological activity THZ2 is an analog of THZ1, a selective inhibitor of CDK7, and its IC50 value is 13.9 nM. THZ2 can effectively inhibit the clone formation and growth of TNBC cells, and its IC50 value is about 10 nM.
target TargetValue CDK7 (Cell-free say) 13.9 nM
TargetValue
CDK7 (Cell-free assay) 13.9 nM
Last Update:2024-04-09 20:49:11
THZ2
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CAS: 1604810-84-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: THZ2  Visit Supplier Webpage Request for quotation
CAS: 1604810-84-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: THZ2 Visit Supplier Webpage Request for quotation
CAS: 1604810-84-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
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Product Name: THZ2 Visit Supplier Webpage Request for quotation
CAS: 1604810-84-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: THZ2 Visit Supplier Webpage Request for quotation
CAS: 1604810-84-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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THZ2
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