Timolol
Timolol
CAS: 26839-75-8
Molecular Formula: C13H24N4O3S
Timolol - Names and Identifiers
Timolol - Physico-chemical Properties
| Molecular Formula | C13H24N4O3S |
| Molar Mass | 316.42 |
| Density | 1.224±0.06 g/cm3(Predicted) |
| Melting Point | 71.5-72.5 °C |
| Boling Point | 487.2±45.0 °C(Predicted) |
| Flash Point | 248.5°C |
| Vapor Presure | 2.62E-10mmHg at 25°C |
| pKa | pKa ～9.2(H2Ot = 25.0) (Uncertain) |
| Refractive Index | 1.548 |
| Use | For open angle glaucoma, aphakic glaucoma and secondary glaucoma, ocular hypertension treatment, also for the treatment of patients with acute myocardial infarction recurrence |
Timolol - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| pharmacological action | timolol is a non-selective β-adrenergic receptor antagonist, which can reduce aqueous humor production without obvious endogenous sympathomimetic activity and local anesthesia effect, and has no direct inhibitory effect on myocardium. Drop eye with 0.5% product once every 12 hours, the effect of lowering intraocular pressure is fast, and the intraocular pressure begins to drop 20-30 minutes after dropping the eye, reaching its peak after 1-2 hours, and can last for more than 12 hours. |
| indications | timolol can be used for primary open-angle glaucoma, some secondary glaucoma, ocular hypertension, some primary angle-closure glaucoma and other glaucoma with ineffective drugs and surgery, the addition of this product can further enhance the intraocular pressure reduction effect. |
| Side effects | The most common eye burning sensation and tingling. It can cause decreased tear secretion, decreased corneal perception, superficial punctate keratopathy, allergic conjunctivitis, etc. After the eye drops are absorbed, bradycardia and arrhythmia may also occur; dizziness, aggravating symptoms of myasthenia gravis, paresthesia, lethargy, insomnia; bronchospasm, respiratory failure, dyspnea, nasal congestion, and cough; cover up diabetic patients Hypoglycemia symptoms after insulin or hypoglycemic drugs. |
| use | for the treatment of open angle glaucoma, aphakic glaucoma, secondary glaucoma, ocular hypertension, and also for the treatment of acute myocardial infarction Patients with recurrence, etc. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:44
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Multiple SpecificationsSpot supply
Product Name: Timolol Visit Supplier Webpage Request for quotationCAS: 26839-75-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Timolol Visit Supplier Webpage Request for quotationCAS: 26839-75-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
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