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Tolimidone

Tolimidone

CAS: 41964-07-2

Molecular Formula: C11H10N2O2

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Tolimidone - Names and Identifiers

Name Tolimidone
Synonyms CP-26154
MLR 1023
Tolimidone
NSC 314335
5-(m-Tolyloxy)pyrimidin-2(1H)-one
5-(3-methylphenoxy)-1H-pyrimidin-2-one
5-(3-Methylphenoxy)-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 5-(3-methylphenoxy)-
CAS 41964-07-2
EINECS 200-258-5

Tolimidone - Physico-chemical Properties

Molecular FormulaC11H10N2O2
Molar Mass202.21
Density1.22
Melting Point163-164℃
Solubility DMSO: soluble15mg/mL (clear solution)
Appearancepowder
Colorwhite to beige
Storage Conditionroom temp
In vitro studyIn an in vitro kinase screening assay, MLR-1023 activated the Non-receptor-linked, Src-associated tyrosine kinase SYN. MLR-1023 increases the Vmax of yn kinase with an EC50 of 63 nM. Activation of this Lyn kinase is independent of the ATP binding site, suggesting that MLR-1023 regulates this kinase through an allosteric mechanism.
In vivo studyMLR-1023 the blood glucose lowering effect mediated is dependent on the activity of Lyn kinase. MLR-1023 is a compound that enhances the insulin receptor and produces a rapid and long-lasting blood glucose lowering effect in animal models of diabetes.

Tolimidone - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36 - Irritating to the eyes
Safety Description26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany3

Tolimidone - Preparation solution concentration reference

 1mg5mg10mg
1 mM4.945 ml24.727 ml49.454 ml
5 mM0.989 ml4.945 ml9.891 ml
10 mM0.495 ml2.473 ml4.945 ml
5 mM0.099 ml0.495 ml0.989 ml
Last Update:2024-01-02 23:10:35
Tolimidone
Supplier List
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: MLR-1023 Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: +86-18821248368
Email: Int06@meryer.com
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Shanghai Amole Biotechnology Co., Ltd.
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CAS: 41964-07-2
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Tolimidone Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
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MedChemExpress (MCE)
Spot supply
Product Name: MLR-1023 Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Tolimidone Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: MLR-1023 Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Tolimidone Request for quotation
CAS: 41964-07-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Tolimidone Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: MLR-1023 Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Tolimidone Visit Supplier Webpage Request for quotation
CAS: 41964-07-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Tolimidone
M-PEG-COOH
575-75-7
Mandelonitrile
10075-52-2
CS-1817
5-Nitrobarbituric acid (Anhydrous type)
Acid Brown 87 (17596)
DIPA
RARECHEM AL BD 1201
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