| Molecular Formula | C11H10N2O2 |
| Molar Mass | 202.21 |
| Density | 1.22 |
| Melting Point | 163-164℃ |
| Solubility | DMSO: soluble15mg/mL (clear solution) |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | room temp |
| In vitro study | In an in vitro kinase screening assay, MLR-1023 activated the Non-receptor-linked, Src-associated tyrosine kinase SYN. MLR-1023 increases the Vmax of yn kinase with an EC50 of 63 nM. Activation of this Lyn kinase is independent of the ATP binding site, suggesting that MLR-1023 regulates this kinase through an allosteric mechanism. |
| In vivo study | MLR-1023 the blood glucose lowering effect mediated is dependent on the activity of Lyn kinase. MLR-1023 is a compound that enhances the insulin receptor and produces a rapid and long-lasting blood glucose lowering effect in animal models of diabetes. |
| Hazard Symbols | Xi - Irritant![]() |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.945 ml | 24.727 ml | 49.454 ml |
| 5 mM | 0.989 ml | 4.945 ml | 9.891 ml |
| 10 mM | 0.495 ml | 2.473 ml | 4.945 ml |
| 5 mM | 0.099 ml | 0.495 ml | 0.989 ml |