Transferrin
Transferrin
CAS: 11096-37-0
Molecular Formula: C16H22N6O4
Transferrin - Names and Identifiers
Transferrin - Physico-chemical Properties
| Molecular Formula | C16H22N6O4 |
| Molar Mass | 362.38368 |
| Water Solubility | Soluble in water (50 mg/ml). |
| Solubility | H2O: 50mg/mL |
| Appearance | Freeze-dried powder |
| Storage Condition | 2-8°C |
| MDL | MFCD00131337 |
Transferrin - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 21 |
| TSCA | Yes |
Transferrin - Reference
| Reference Show more | 1. Lv Juan, Zhou Gang, Li Zhenlian, Du Yan, Zhu Ye Qing. Determination of relative molecular mass distribution of peptides in peptone by gel filtration chromatography [J]. Journal of Food Safety and Quality Inspection 2020 11(15):5131-5136. 2. Yang Kai, Li Yipeng, Liu Yingfu, Cheng Yuanchi, Tang Fengwu, Liang Bing, Xu Zhongwei, Chen Xuyi. Optimization of culture conditions for rat cortical oligodendrocytes [J]. China Tissue Engineering Research, 2016,20(29):4328-4333. 3. Jiang Li, Tan Yi, Wang Jun. Preparation of transferrin modified neferine nanoliposomes and investigation of brain targeting [J]. Chinese Pharmacist, 2019, 22(03):447-450. 4. Luo Mingzhi, Yu Peili, Jin Yang, et al.. Effects of sanguinarine on biomechanical properties of rat airway smooth muscle cells [J]. Journal of Biomedical Engineering, 2018, v.35(04):89-97. 5. Xiao Yuhan, Hu Yue, Huang Peili. Fluorescence spectroscopy and isothermal titration calorimetry to study the interaction between cadmium telluride quantum dots and transferrin [J]. Journal of Toxicology, 2020,34(06):449-453. 6. Yang Zhuoyi, Chen Hui, Bai Siyi, Pamela Palhati, Hou Jingli, Yuan Yunsheng. Phosphorylation Proteomic Study on Hepatocyte Injury Induced by Concanavalin A [J]. Journal of Shanghai Jiaotong University (Medical Edition),2021,41(01):1-7. 7. Lu Juan, Zhou Gang, Li Zhenlian, Du Yan, Zhu Yeqing. Determination of relative molecular mass distribution of peptides in peptone by gel filtration chromatography [J]. Journal of Food Safety and Quality Inspection, 2020,11(15):5131-5136. 8. Zhu, Chunling, et al. "Construction of synergistic therapy system with multiple therapeutic effects based on CuS @ Tf nanodots." Journal of Inorganic Biochemistry 209 (2020): 111100.https://doi.org/10.1016/j.jinorgbio. 2020.111100 9. Guichun Mo, Xinxin He, Chunqin Zhou, Dongmei Ya, Jinsu Feng, Chunhe Yu, Biyang Deng,A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO2@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha- 10. Zhang, Aitang, et al. "A Target‐Directed Chemo‐Photothermal System Based on Transferrin and Copolymer‐Modified MoS2 Nanoplates with pH‐Activated Drug Release." Chemistry-A European Journal 23.47 (2017): 11346-11356.https://doi.org/10.1002/chem.201701916 11. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo, Jingquan Liu,An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control 12. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo, Jingquan Liu,An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control 13. [IF=13.273] Aitang Zhang et al."An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually controlled drug release."Chem Eng J. 2018 Jun;342:120 14. [IF=9.518] Guichun Mo et al."A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO2@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha-fetoprotein."Biosens Bioelectron. 2019 Feb;126:558 15. [IF=6.331] Wei Zhao et al."Transferrin-decorated, MoS2-capped hollow mesoporous silica nanospheres as a self-guided chemo-photothermal nanoplatform for controlled drug release and thermotherapy."J Mater Chem B. 2017 Sep;5(35):7403-7414 16. [IF=10.618] Cai-Feng Shi et al."Ultrasensitive plasmon enhanced Raman scattering detection of nucleolin using nanochannels of 3D hybrid plasmonic metamaterial."Biosens Bioelectron. 2021 Apr;178:113040 17. [IF=7.1] Rui Duan et al."Integrating boronate affinity controllable-oriented surface imprinting nylon wire and pH-triggered allochroic-graphene oxide for ultrasensitive detection of glycoprotein."Sensor Actuat B- Chem. 2021 Mar;330:129310 18. [IF=5.875] Yanyan Yin et al."Cascade catalytic nanoplatform based on ions interference strategy for calcium overload therapy and ferroptosis."Int J Pharmaceut. 2021 Sep;606:120937 19. [IF=4.155] Chunling Zhu et al."Construction of synergistic therapy system with multiple therapeutic effects based on CuS@Tf nanodots."J Inorg Biochem. 2020 Aug;209:111100 20. [IF=2.649] Xingzhen Zhang et al."Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma."Med Sci Monitor. 2019; 25: 9737-9751 21. [IF=9.229] Miaomiao Han et al."Amyloid Protein-Biofunctionalized Polydopamine Nanoparticles Demonstrate Minimal Plasma Protein Fouling and Efficient Photothermal Therapy."Acs Appl Mater Inter. 2022;XXXX(XXX):XXX-XXX 22. [IF=6.057] Zhi-Heng Pan et al."Poly(caffeic acid)-coated molecularly imprinted magnetic nanoparticles for specific and ultrasensitive detection of glycoprotein."Talanta. 2022 May;241: 123240 Transferrin freeze-dried powder needs to be stored in a refrigerated state and dissolved before use. Generally, PBS or other suitable solvents are used to dissolve transferrin freeze-dried powder into a storage solution at room temperature with a concentration of 0.5-2.0 mg/ml, and then filtered with a sterile filter membrane. The filtrate can be stored at 2-8 ℃ for 30 days under sterile conditions. |
Transferrin - Introduction
Transferrin is the main iron transfer protein in plasma, providing the required iron for cell differentiation and cell metabolism. Studies have found that all cell growth cannot be separated from transferrin. Not only does maintaining normal cell metabolism depend on iron in biologically active form, iron is also a cofactor of some enzymes, such as RNA polymerase and DNA synthetase. It is also an important part of hemoglobin.
Last Update：2022-10-16 17:12:02
Transferrin - Instructions for Use
Transferrin is essential for most cell lines to grow in serum-free medium, and studies have shown that transferrin in the saturated iron form is the most effective form for promoting cell growth. For hybridomas, adherent cells and suspension cell lines, the medium concentration of transferrin should be maintained at 0.5-100 μg/ml during cell culture. For different cell lines, the most appropriate concentration needs to be selected.
Last Update：2023-08-16 21:32:38
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