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Tunicamycin

Tunicamycin

CAS: 11089-65-9

Molecular Formula: C37H60N4O16

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Tunicamycin - Names and Identifiers

Name Tunicamycin
Synonyms Nsc177382
Aids010655
NSC 177382
Tunicamycin
Aids-010655
TunicaMycin coMplex
InSolution? Tunicamycin,
TUNICAMYCIN, STREPTOMYCES LYSOSUPERFICUS
TUNICAMYCIN, STREPTOMYCES IYSOSUPERFICUS
TunicaMycin froM StreptoMyces lysosuperficus
(E)-N-[(2R,3R,4R,5R,6R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6-[2-[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]-2-hydroxy-ethyl]-4,5-dihydroxy-tetrahydropyran-3-yl]-5-methyl-hex-2-enamide
(E)-N-[(2S,3R,4R,5R,6R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6-[2-[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]-2-hydroxy-ethyl]-4,5-dihydroxy-tetrahydropyran-3-yl]-5-methyl-hex-2-enamide
CAS 11089-65-9
EINECS 601-012-4
InChI InChI=1/C30H46N4O16/c1-11(2)5-4-6-16(38)32-19-23(43)20(40)14(47-29(19)50-28-18(31-12(3)36)22(42)21(41)15(10-35)48-28)9-13(37)26-24(44)25(45)27(49-26)34-8-7-17(39)33-30(34)46/h4,6-8,11,13-15,18-29,35,37,40-45H,5,9-10H2,1-3H3,(H,31,36)(H,32,38)(H,33,39,46)/b6-4+/t13?,14-,15-,18-,19-,20+,21-,22-,23-,24+,25-,26-,27-,28-,29+/m1/s1
InChIKey YJQCOFNZVFGCAF-WPTOCQRYSA-N

Tunicamycin - Physico-chemical Properties

Molecular FormulaC37H60N4O16
Molar Mass816.89
Density1.57g/cm3
Melting Point234-235℃ (decomposition)
Specific Rotation(α)D20 +52° (c = 0.5 in pyridine)
Flash Point87℃
Solubility Soluble in water (partly miscible), alkaline water, pyridine, hot methanol, DMSO (>10 mg
AppearancePowder
ColorWhite
BRN6888090
Storage Condition2-8°C
StabilityStable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
SensitiveMoisture & Light Sensitive
Refractive Index1.649
MDLMFCD00065709
Physical and Chemical Properties

UseAntibiotic drugs, antibiotics, microbial metabolites, biochemical reagents
In vivo study Tunicamycin (0.1 mg/kg or 0.5 mg/kg) treatment dramatically suppresses tumor growth in the CD133 +/- MHCC97L cells xenograft model (BALB/c ( nu/nu ) mice).

Tunicamycin - Risk and Safety

Risk Codes28 - Very Toxic if swallowed
Safety DescriptionS28 - After contact with skin, wash immediately with plenty of soap-suds.
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 3462 6.1/PG 2
WGK Germany3
RTECSYO7980200
FLUKA BRAND F CODES8-10-18-21
HS Code29419090
Hazard Class6.1(a)
Packing GroupII

Tunicamycin - Reference

Reference
Show more
1. [IF=4.044] Yang Yong et al."Endoplasmic reticulum stress may activate NLRP3 inflammasomes via TXNIP in preeclampsia."Cell Tissue Res. 2020 Mar;379(3):589-599
Tunicamycin
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 11089-65-9
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Tunicamycin from Streptomyces sp. Visit Supplier Webpage Request for quotation
CAS: 11089-65-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Featured ProductsSpot supply
Product Name: Tunicamycin Visit Supplier Webpage Request for quotation
CAS: 11089-65-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Featured ProductsSpot supply
Product Name: Tunicamycin from Streptomyces lysosuperficus Visit Supplier Webpage Request for quotation
CAS: 11089-65-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Tunicamycin Request for quotation
CAS: 11089-65-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Tunicamycin Visit Supplier Webpage Request for quotation
CAS: 11089-65-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Tunicamycin streptomyces lysosuperficus Visit Supplier Webpage Request for quotation
CAS: 11089-65-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
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