Val-cit-PAB-OH
Val-cit-PAB-OH
CAS: 159857-79-1
Molecular Formula: C18H29N5O4
Val-cit-PAB-OH - Names and Identifiers
Val-cit-PAB-OH - Physico-chemical Properties
| Molecular Formula | C18H29N5O4 |
| Molar Mass | 379.45 |
| Density | 1.243±0.06 g/cm3(Predicted) |
| Melting Point | 168 °C(dec.) |
| Boling Point | 715.0±60.0 °C(Predicted) |
| Solubility | DMSO :59 mg/mL (155.49 mM) |
| pKa | 13.75±0.46(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Physical and Chemical Properties | Bioactive Val-cit-PAB-OH is a degradable ADC linker. |
| Use | The VAL-CIT-PAB is used as a reagent to prepare cell penetrating peptide GRP78 ligand for tumor cell-specific prodrug therapy, and to prepare monomethylvaline derivative ligand and antibody for cancer therapy. |
Val-cit-PAB-OH - Upstream Downstream Industry
Val-cit-PAB-OH - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.635 ml | 13.177 ml | 26.354 ml |
| 5 mM | 0.527 ml | 2.635 ml | 5.271 ml |
| 10 mM | 0.264 ml | 1.318 ml | 2.635 ml |
| 5 mM | 0.053 ml | 0.264 ml | 0.527 ml |
Last Update：2024-01-02 23:10:35
Val-cit-PAB-OH - Reference Information
| Use | VAL-CIT-PAB is used as a reagent to prepare the cell penetrating peptide GRP78 ligand for tumor cell-specific prodrug therapy, and to prepare monomethylvaline derivative ligands and antibodies for cancer treatment. |
| biological activity | Val-cit-PAB-OH is a degradable ADC linker. |
| target | Cleavable |
Last Update：2024-04-09 21:54:55
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View History
Val-cit-PAB-OH
10387-13-0
Quinuclidin-3-ol
甲氧奈丙酸钠
1537866-49-1
Phthalocyanine Green
(+)-MURAMIC ACID
155521-46-3
13715-23-6
Methyl (diethylphosphono)acetate
10387-13-0
Quinuclidin-3-ol
甲氧奈丙酸钠
1537866-49-1
Phthalocyanine Green
(+)-MURAMIC ACID
155521-46-3
13715-23-6
Methyl (diethylphosphono)acetate
Raw Materials for Val-cit-PAB-OH
L-Ornithinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
H-Cit-PABA
FMOC-L-Valine
FMOC-VAL-OSU
Fmoc-Cit-PABA
H-Cit-PABA
FMOC-L-Valine
FMOC-VAL-OSU
Fmoc-Cit-PABA
Downstream Products for Val-cit-PAB-OH
MC-Val-Cit-PAB
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-