azelastine
Azelastine
CAS: 58581-89-8
Molecular Formula: C22H24ClN3O
azelastine - Names and Identifiers
azelastine - Physico-chemical Properties
| Molecular Formula | C22H24ClN3O |
| Molar Mass | 381.9 |
| Density | 1.1505 (rough estimate) |
| Melting Point | 111 - 115°C |
| Boling Point | 533.9±60.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | pKa 9.82(H2O t=25 I=0.025) (Uncertain) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5790 (estimate) |
| Physical and Chemical Properties | Oils. Soluble in dichloromethane. Monohydrate: Crystallized from ethanol-water. Two different crystal forms can be identified. Azogastine hydrochloride (Azelastine Hydrochloride):C22H24ClN3O?HCl. [79307-93-0]. White crystalline powder, odorless, bitter taste. Soluble in chloroform, dichloromethane or glacial acetic acid, slightly soluble in methanol, slightly soluble in absolute ethanol or water, insoluble in acetone or ether. Melting point 225~229 ℃. Acute toxicity LD50 male and female mice, male and female rats, male and female guinea pigs (mg/kg):124,139,310,417,126,130 orally; 36.5,35.5,26.9,30.3,23.0,24.8 intravenous injection; 597.0,57.2,143.0,115.0,46.2,52.2 intramuscular injection; 63.0,54.2,66.5,59.6. 41.0.37.3 Subcutaneous injection. |
azelastine - Risk and Safety
| Toxicity | LD50 orl-rat: 310 mg/kg ARZNAD 31,1184,81 |
azelastine - Reference
| Reference Show more | 1. Li, Meng, et al. "Chiral separation of five antihistamine drug enantiomers and enantioselective pharmacokinetic study of carbinoxamine in rat plasma by HPLC-MS/MS." New Journal of Chemistry 44.15 (2020): 5819-5827.https://doi.org/10.1039/D0NJ00095G |
azelastine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.618 ml | 13.092 ml | 26.185 ml |
| 5 mM | 0.524 ml | 2.618 ml | 5.237 ml |
| 10 mM | 0.262 ml | 1.309 ml | 2.618 ml |
| 5 mM | 0.052 ml | 0.262 ml | 0.524 ml |
Last Update：2024-01-02 23:10:35
Supplier List
Featured ProductsSpot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one Request for quotationCAS: 58581-89-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one Request for quotationCAS: 58581-89-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Azelastine Visit Supplier Webpage Request for quotationCAS: 58581-89-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History