dimethomorph
dimethomorph
CAS: 110488-70-5
Molecular Formula: C21H22ClNO4
dimethomorph - Names and Identifiers
dimethomorph - Physico-chemical Properties
| Molecular Formula | C21H22ClNO4 |
| Molar Mass | 387.86 |
| Density | 1.231g/cm3 |
| Melting Point | 125-149°C |
| Boling Point | 584.9°C at 760 mmHg |
| Flash Point | 307.5°C |
| Water Solubility | 50 mg l-1 (20-23 °C) |
| Vapor Presure | 1 x 10-6 Pa (25 °C) |
| Appearance | neat |
| Merck | 13,3248 |
| BRN | 8794474 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.58 |
| Physical and Chemical Properties | Melting point 125-149°C |
| Use | Mainly used to control grape downy mildew and potato late blight, usually mixed with Mancozeb |
dimethomorph - Risk and Safety
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | 51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | QE0478300 |
| Toxicity | LD50 in rats (mg/kg): 321 i.p.; 3900 orally; >5000 dermally; LC50 (4-hr inhalation): >4.2 mg/ml (Veenstra, Owen) |
dimethomorph - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| fungicide | dimethomorph is a broad-spectrum fungicide of morpholine. it has a unique mode of action against fungi of phyctophthora and phytophthora, mainly causing the decomposition of sporangium walls, thus causing the death of the bacteria. Except for zoospore formation and spore swimming period, it has an effect on all stages of the life history of oomycetes, especially in the formation stage of sporangia and oospore. It is more sensitive at extremely low concentrations ( |
| control object and application method | 1. control cucumber, balsam pear downy mildew, cruciferous vegetable downy mildew before or at the beginning of the disease, 69% grams of manganese zinc 1500-1995 grams per hectare (69-92 grams of active ingredient), and the spraying amount is 900-1200 liters. Spray once every 7-10 days, and spray 3-4 times continuously. 2. Control pepper blight, grape downy mildew, tobacco black shank, potato late blight before or at the beginning of the onset of spraying, 69% grams of manganese zinc 1995-2505 grams (active ingredient 92-115 grams) per hectare, the spraying amount is 900-1200 liters, and the grape is 2250-3000 liters per metric. Spray once every 7-10 days, and spray 3-4 times continuously. |
| toxicity | dimethomorph is a low-toxicity fungicide according to China's pesticide toxicity classification standard. Acute oral LD50 is greater than 3900 mg/kg in rats, percutaneous LD50 is greater than 2000 mg/kg, and acute inhalation LC50 is greater than 4.24 mg/L in rats. It has no irritation to rabbit skin, slight irritation to eyes, and no sensitization to guinea pigs. Under the test conditions, there was no mutagenic, teratogenic and carcinogenic effects. Rats were fed for 90 days with no effective dose of 200 mg/kg. The drug is moderately toxic to fish, trout acute LC503 mg/L (96 hours), carp LC5014 mg/L (96 hours), Daphnia LC5048 mg/L (48 hours). Under normal use, it is low toxic to bees, and the oral LD50 is greater than 100 μg/head. It has no toxic effect on silkworm. Low toxicity to birds, acute oral LD50 of wild ducks is greater than 2000 mg/kg. Under anaerobic conditions, the half-life in soil is 20 days; under aerobic conditions, the half-life in soil is 50 days. Under ultraviolet light conditions, the E isomer of this compound can be converted into the effective isomer Z. It decomposes quickly in crops and does not accumulate in the environment. The drug has no effect on natural enemies, and the non-effect dose on earthworms is 1000 mg/kg soil. Acute oral LD502400 mg/kg and acute percutaneous LD50 greater than 2000 mg/kg in rats. Slight irritation to eyes, no irritation to skin. |
| precautions | 1. when cucumbers, peppers, cruciferous vegetables and other young hours, the spray amount and dosage are low. Spray to make the liquid cover the blades evenly. 2. Wear protective clothing during application to avoid direct contact with various parts of the body. 3. If the medicine is contaminated with skin, rinse with soap and water. If you take it by mistake, don't vomit and send it to the hospital for treatment as soon as possible. The drug has no antidote and is symptomatic. 4. The drug should be stored in a cool, dry and away from feed and children. 5. Do not use dimethomorph (anke manganese zinc) more than 4 times per season. Pay attention to the use of other fungicides with different mechanisms of action and their rotation application. |
| synthesis method | step 1: xylene and acetic anhydride are stirred and dropwise added with morpholine at normal temperature, slowly raised to 110 ℃ after dropwise addition, refluxed and kept for 5 hours, then dissolved into a distillation kettle and by-product acetic acid. the residual part in the kettle is intermediate acetylmorpholine with a content greater than or equal to 99% and a yield greater than or equal to 90.2%. Step 2: Put xylene, E-benzote and sodium amide into the reaction kettle, stir and add acetylmorpholine dropwise when the temperature is raised to 100 ℃, add dimethomorph dropwise after the drop is raised to 110 ℃ and refluxed for 2 hours, pass it into a water washing kettle to separate waste alkali liquor after the temperature is lowered to 80 ℃, wash to neutral, pass it into a distillation kettle to recover xylene, and centrifuge and dry to obtain dimethomorph with a content of 95% or more and a yield of 76.6% or more. In this method, sodium amide is used to replace sodium tert-butoxide of traditional technology, which greatly improves the reaction speed, shortens the reaction time from 10h to 2h, and greatly improves the production efficiency. |
| Use | Mainly used to control grape downy mildew and potato late blight, usually mixed with mancozeb |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 22:01:16
Supplier List
Featured ProductsSpot supply
Product Name: Dimethomorph Request for quotationCAS: 110488-70-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: dimethomorph Request for quotation
CAS: 110488-70-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 110488-70-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple Specifications
Product Name: Dimethomorph(mixture of isomer) Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: Dimethomorph Request for quotation
CAS: 110488-70-5
Tel: 025-52110956
Email: lvmu@lskhsw.com
Mobile: 15195951328
QQ: 2468914230
Send QQ message
CAS: 110488-70-5
Tel: 025-52110956
Email: lvmu@lskhsw.com
Mobile: 15195951328
QQ: 2468914230
Featured ProductsSpot supply
Product Name: Dimethomorph Request for quotationCAS: 110488-70-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Dimethomorph Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: dimethomorph Request for quotation
CAS: 110488-70-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 110488-70-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple Specifications
Product Name: Dimethomorph(mixture of isomer) Visit Supplier Webpage Request for quotationCAS: 110488-70-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: Dimethomorph Request for quotation
CAS: 110488-70-5
Tel: 025-52110956
Email: lvmu@lskhsw.com
Mobile: 15195951328
QQ: 2468914230Send QQ message
CAS: 110488-70-5
Tel: 025-52110956
Email: lvmu@lskhsw.com
Mobile: 15195951328
QQ: 2468914230
View History