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m-Hydroxyacetophenone

m-Hydroxyacetophenone

CAS: 121-71-1

Molecular Formula: C8H8O2

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m-Hydroxyacetophenone - Names and Identifiers

Name m-Hydroxyacetophenone
Synonyms m-Acetylphenol
3-Hydroxyacetophenon
m-Hydroxyacetophenone
m-Hydroxyacetophenonel
META-HYDROXYACETOPHENONE
Ethanone, 1-(3-hydroxyphenyl)-
3'-Hydroxyacetophenone 3-Acetylphenol m-Acetylphenol
CAS 121-71-1
EINECS 204-494-0
InChI InChI=1/C8H8O2/c1-6(9)7-3-2-4-8(10)5-7/h2-5,10H,1H3

m-Hydroxyacetophenone - Physico-chemical Properties

Molecular FormulaC8H8O2
Molar Mass136.15
Density1.1
Melting Point94-97℃
Boling Point296℃
Flash Point296°C
Water SolubilitySoluble in alcohol. Insoluble in water.
AppearanceWhite crystal
Storage ConditionRoom Temprature
MDLMFCD00002298
Physical and Chemical PropertiesDensity 1.10
melting point 94-97°C
boiling point 296°C
UseUsed in organic synthesis, is also an intermediate of the drug Phenylephrine

m-Hydroxyacetophenone - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection

m-Hydroxyacetophenone - Upstream Downstream Industry

Raw Materials3-Aminoacetophenone
1-[3-(methoxymethoxy)phenyl]ethanone
1-[3-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]ethanone
3'-IODOACETOPHENONE
3-Methoxyacetophenone
Downstream Products4-Hydroxyphenylacetamide
APLPHA-BROMO-M-BENZOYLOXYACETOPHENONE
1-(3-hydroxyphenyl)-2-[methyl(phenylmethyl)amino]ethan-1-one
1-(5-hydroxy-2-nitrophenyl)ethanone
2-Bromo-3′-hydroxyacetophenone
3-ACETAMIDOPHENOL

m-Hydroxyacetophenone - Security information

WGK Germany 3
Hazard Note Harmful/Irritant
TSCA Yes
customs code 29143990
Last Update:2024-04-10 22:29:15

m-Hydroxyacetophenone - Nature

storage conditions Inert atmosphere,Room Temperature
solubility 22g/l
acidity coefficient (pKa) 9.19(at 25℃)
morphology Crystalline Powder
color Beige-brown
water solubility Soluble in alcohol. Insoluble in water.
BRN 2040676
InChIKey LUJMEECXHPYQOF-UHFFFAOYSA-N
NIST chemical information Ethanone, 1-(3-hydroxyphenyl)-(121-71-1)
EPA chemical information Ethanone, 1-(3-hydroxyphenyl)- (121-71-1)
Last Update:2024-04-09 01:59:49

m-Hydroxyacetophenone - Production method

It is obtained by the reaction of m-aminoacetophenone and sodium nitrite. Add water and concentrated sulfuric acid into the reaction pot, add m-aminoacetophenone under stirring, and then add sodium nitrite aqueous solution dropwise under cooling, keep the temperature at 8-10 ℃, slowly raise the temperature to above 90 ℃ after adding, and continue stirring for 1h. The solid is precipitated by cooling, filtered, and the obtained crude product is recrystallized with hot water to obtain m-hydroxyacetophenone. 65% yield.

Last Update:2024-04-09 19:04:55
m-Hydroxyacetophenone
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: 3'-Hydroxyacetophenone Visit Supplier Webpage Request for quotation
CAS: 121-71-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
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CAS: 121-71-1
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
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Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: m-Hydroxyacetophenone Request for quotation
CAS: 121-71-1
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: m-Hydroxyacetophenone Request for quotation
CAS: 121-71-1
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
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Nantong Reform Petro-Chemical CO., LTD.
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CAS: 121-71-1
Tel: +86-13776910623
Email: r@reformchem.com­
Mobile: +86-13776910623
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Wechat: chemical6666 
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: 3'-Hydroxyacetophenone Request for quotation
CAS: 121-71-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Changsha Changtang import and Export Co., Ltd.
Product Name: m-Hydroxyacetophenone Request for quotation
CAS: 121-71-1
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472 Click to send a QQ message
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
MedChemExpress (MCE)
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CAS: 121-71-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 3'-Hydroxyacetophenone Visit Supplier Webpage Request for quotation
CAS: 121-71-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
SKYRUN INDUSTRIAL CO.,LTD
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Product Name: 3'-Hydroxyacetophenone Visit Supplier Webpage Request for quotation
CAS: 121-71-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
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View History
m-Hydroxyacetophenone
Raw Materials for m-Hydroxyacetophenone
3-Aminoacetophenone
1-[3-(methoxymethoxy)phenyl]ethanone
1-[3-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]ethanone
3'-IODOACETOPHENONE
3-Methoxyacetophenone
Downstream Products for m-Hydroxyacetophenone
4-Hydroxyphenylacetamide
APLPHA-BROMO-M-BENZOYLOXYACETOPHENONE
1-(3-hydroxyphenyl)-2-[methyl(phenylmethyl)amino]ethan-1-one
1-(5-hydroxy-2-nitrophenyl)ethanone
2-Bromo-3′-hydroxyacetophenone
3-ACETAMIDOPHENOL
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