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protostemotinine

protostemotinine

CAS: 169534-85-4

Molecular Formula: C23H29NO6

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protostemotinine - Names and Identifiers

Name protostemotinine
Synonyms ProtosteMotinine
protostemotinine
(3S,11S,11aS)-3'-Methoxy-4',9-dimethyl-3-[(2S,4S)-4-methyl-5-oxotetrahydrofuran-2-yl]-2,3,5,6,7,8-hexahydro-1H,5'H,10H-spiro[cyclopenta[b]pyrrolo[1,2-a]azepine-11,2'-furan]-5',10-dione
(3S,11S,11aS)-3'-Methoxy-4',9-dimethyl-3-[(2S,4S)-4-methyl-5-oxot etrahydro-2-furanyl]-2,3,5,6,7,8-hexahydro-1H,5'H,10H-spiro[cyclo penta[b]pyrrolo[1,2-a]azepine-11,2'-furan]-5',10-dione
Spiro[1H-cyclopenta[b]pyrrolo[1,2-a]azepine-11(10H),2'(5'H)-furan]-5',10-dione, 2,3,5,6,7,8-hexahydro-3'-methoxy-4',9-dimethyl-3-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (2'S,3S,11aS)-
spiro[1H-cyclopenta[b]pyrrolo[1,2-a]azepine-11(10H),2'(5'H)-furan]-5',10-dione, 2,3,5,6,7,8-hexahydro-3'-methoxy-4',9-dimethyl-3-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (3S,11S,11aS)-
CAS 169534-85-4
InChI InChI=1/C23H29NO6/c1-12-11-17(29-20(12)26)16-8-9-22-15(7-5-6-10-24(16)22)13(2)18(25)23(22)19(28-4)14(3)21(27)30-23/h12,16-17H,5-11H2,1-4H3/t12-,16-,17-,22-,23+/m0/s1

protostemotinine - Physico-chemical Properties

Molecular FormulaC23H29NO6
Molar Mass415.48
Density1.31±0.1 g/cm3 (20 ºC 760 Torr)
Boling Point690.7±55.0 °C at 760 mmHg
Solubility Slightly soluble (3.9g/L) (25°C)
AppearanceWhite crystalline powder
Storage Condition2-8℃
Refractive Index1.59
MDLMFCD14155631
Physical and Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Baibu.

protostemotinine - Reference Information

interaction 1. combined with baixiaoamine, cyclophosphamide, methotrexate, glorimycin, hydralazine, hexahydroxyquaternary, mecamin, nitrofurantoin, ercoxonine, oral contraceptives, chlorothiazide and butazone, etc., can aggravate dyspnea.

2. combined with ferrous sulfate, sulfa, aminophylline, acidogenic drugs, digitalis and levodopa, can cause nausea and vomiting.
adverse reactions 1. toxic reactions: nausea and vomiting, abdominal pain, diarrhea, epistaxis, biliary colic, dizziness, headache, pale complexion, dyspnea, etc. are occasionally seen after oral administration. In severe cases, convulsions, coma, and even death due to paralysis of the respiratory center may occur.

2. allergic reaction: small red miliary rash appeared on the skin, itching is unbearable.
biological activity Protostemotinine is an alkaloid isolated from Stemona sessilifolia.
chemical properties white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Baibu.
use protopepenobase has anti-inflammatory, anti-inflammatory and anti-allergic effects.
Last Update:2024-04-09 20:49:11
protostemotinine
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Shanghai Yuanye Bio-Technology Co., Ltd.
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Email: 3008007409@qq.com
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