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2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid

CAS: 68399-81-5

Molecular Formula: C7H17NO7S

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tapso - Names and Identifiers

Name 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid
Synonyms TAPSO
TAPSO Buffer
TAPSO, for biochemistry
N-[Tris(hydroxymethyl)metyl]-3-amino-2-hydroxypropanesulfonic acid
N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid
TAPSO(2-Hydroxy-3-[tris(hydroxyMethylaMino]-1 propanesulfonic acid)
N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydro-xypropanesulfonic acid
3-[N-Tris-(hydroxyMethyl)MethylaMino]-2-hydroxypropanesulphonic acid(TAPSO)
2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid
(2R)-2-hydroxy-3-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonio}propane-1-sulfonate
(2S)-2-hydroxy-3-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ammonio}propane-1-sulfonate
3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}-2-hydroxypropane-1-sulfonic acid
CAS 68399-81-5
EINECS 269-993-8
InChI InChI=1/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)/t6-/m0/s1

tapso - Physico-chemical Properties

Molecular FormulaC7H17NO7S
Molar Mass259.28
Density1.07607 g/cm3(Temp: 25.00 °C)
Melting Point224-229°C (dec.)
Water Solubilitysoluble
Solubility H2O: 1M at20°C, clear, colorless
AppearanceWhite powder
ColorOff-white to yellow
Merck13,9148
BRN2113949
pKa7.6(at 25℃)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
Refractive Index1.589
MDLMFCD00038352
UseBiological buffer

tapso - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany3
TSCAYes
HS Code29221990
Hazard ClassIRRITANT

tapso - Reference Information

application N-tris (hydroxymethyl) methinoate -2-hydroxypropanesulfonic acid can be used as an ionic buffer, and can also be used as an organic synthesis intermediate and a pharmaceutical intermediate. It is mainly used in laboratory research and development processes and chemical and pharmaceutical synthesis processes.
Preparation N-tris (hydroxymethyl) methionine-2-hydroxypropanesulfonic acid is prepared as follows: 242.28 grams (2 moles) of tris (hydroxymethyl) aminomethane, A mixture of 500 ml of water and 196.5g (1 mol) of sodium 3-chloro-2-hydroxypropyl sulfonate is put into a 1 liter 2-neck flask with a stirrer and condenser. Stir the mixture vigorously under reflux for 3 hours. After cooling to 25°C, the solution is passed through a cation exchange resin column in the form of Dowex50 and hydrogen to remove sodium cations and form free acids. The eluent from the column evaporates into heavy oil under vacuum. After dilution with alcohol, the product crystallizes from the solution, is filtered and washed with alcohol and dried. 160 grams of the white product N-tris (hydroxymethyl) methine-2-hydroxypropanesulfonic acid was obtained.
use biological buffer
EPA chemical information information provided by: ofmpub.epa.gov (external link)
Last Update:2024-04-09 19:05:03
tapso
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Shanghai Macklin Biochemical Co., Ltd
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid Visit Supplier Webpage Request for quotation
CAS: 68399-81-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
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Product Name: 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid Request for quotation
CAS: 68399-81-5
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Jiangsu Pules Biotechnology Co.,Ltd.
Spot supply
Product Name: 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid Request for quotation
CAS: 68399-81-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propanesulphonic acid Request for quotation
CAS: 68399-81-5
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685 Click to send a QQ message
Wechat: chemical6666
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonicAcid Request for quotation
CAS: 68399-81-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid Visit Supplier Webpage Request for quotation
CAS: 68399-81-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: TAPSO Visit Supplier Webpage Request for quotation
CAS: 68399-81-5
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: TAPSO Visit Supplier Webpage Request for quotation
CAS: 68399-81-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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