二氯四氨
4-Amino-2-chloro-6, 7-dimethoxyquinazoline
CAS: 23680-84-4
Molecular Formula: C10H10ClN3O2
二氯四氨 - Names and Identifiers
二氯四氨 - Physico-chemical Properties
| Molecular Formula | C10H10ClN3O2 |
| Molar Mass | 239.66 |
| Density | 1.5062 (rough estimate) |
| Melting Point | 262-268°C (dec.)(lit.) |
| Boling Point | 374.0±42.0 °C(Predicted) |
| Flash Point | 180°C |
| Water Solubility | 1.418g/L at 25℃ |
| Solubility | DMSO (Sparingly, Heated), Methanol (Slightly, Heated) |
| Vapor Presure | 0Pa at 25℃ |
| Appearance | neat |
| Color | White to Off-White |
| BRN | 747463 |
| pKa | 4.35±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.5500 (estimate) |
| MDL | MFCD00051734 |
| Physical and Chemical Properties | Melting point 262-278°C (dec.) |
| Use | As a drug intermediate of alfuzosin hydrochloride |
二氯四氨 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
二氯四氨 - Reference Information
| LogP | 1.5 at 25℃ |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| uses | pharmaceutical intermediates are used to synthesize prazosin, doxazosin, terazosin and other drugs.. used as an intermediate of alfuzosin hydrochloride used to synthesize prazosin, doxazosin, terazosin, alfuzosin and other drugs |
Last Update：2024-04-09 20:15:17
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