吗啉乙醇
N-(2-Hydroxyethyl)morpholine
CAS: 622-40-2
Molecular Formula: C6H13NO2
吗啉乙醇 - Names and Identifiers
吗啉乙醇 - Physico-chemical Properties
| Molecular Formula | C6H13NO2 |
| Molar Mass | 131.17 |
| Density | 1.083g/mLat 25°C(lit.) |
| Melting Point | -1 °C |
| Boling Point | 227°C757mm Hg(lit.) |
| Flash Point | 211°F |
| Water Solubility | miscible |
| Vapor Presure | 2.44-7Pa at 20-25℃ |
| Appearance | Liquid |
| Color | Clear colorless to yellow |
| BRN | 104375 |
| pKa | 14.88±0.10(Predicted) |
| PH | 10.7 (100g/l, H2O, 20℃) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Explosive Limit | 1.5-9.8%(V) |
| Refractive Index | n20/D 1.476(lit.) |
| Physical and Chemical Properties | The boiling point of 227 deg C (100.9kPa), the relative density of 1.0710(20/4 deg C), the refractive index of 1.4763. Flash point 99 °c. Soluble in water and ethanol. |
吗啉乙醇 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 1 |
| RTECS | QE3510000 |
| FLUKA BRAND F CODES | 10-23 |
| TSCA | Yes |
| HS Code | 29349990 |
吗啉乙醇 - Reference Information
| LogP | -1.32 at 25℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | 2-morpholine ethanol is a colorless liquid, which is a morpholine derivative and is used to prepare an ester prodrug of naproxen. It can induce repair in rat hepatocyte primary cultures/DNA. |
| Use | for organic synthesis. is a very important class of chemical pharmaceutical intermediates, can be used for the synthesis of the following pharmaceutical products: mycophenolate, mycophenolate, Pholcodine; Pinaveriumbromidide. |
| production method | is obtained by addition of morpholine and ethylene oxide. Ethylene oxide gas was introduced into the morpholine for reaction, and the temperature was controlled at 20 ° C. Or lower. The residual liquid was distilled under reduced pressure, and the fractions at 122-126 ℃(1.33kPa) were collected to obtain morpholine ethanol. |
Last Update：2024-04-09 02:00:10
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