尼罗红
尼罗红(Nile Red)
CAS: 7385-67-3
化学式: C20H18N2O2
| 中文名 | 尼罗红 |
| 英文名 | Nile Red |
| 别名 | 尼罗丝 尼罗红 尼罗红, 用于荧光分析 |
| 英文别名 | NILE RED Nile Red NILE BLUE A OXAZONE 9-(diethylamino)-5h-benzo[a]phenoxazin-5-on 9-(diethylamino)benzo[a]phenoxazin-5(5H)-one |
| CAS | 7385-67-3 |
| EINECS | 230-966-0 |
| 化学式 | C20H18N2O2 |
| 分子量 | 318.37 |
| InChIKey | VOFUROIFQGPCGE-UHFFFAOYSA-N |
| 密度 | 1.1871 (rough estimate) |
| 熔点 | 203-205 °C(lit.) |
| 沸点 | 457.53°C (rough estimate) |
| 溶解度 | 溶于水 (部分混溶) 和甲醇 (1 mg/ml)。 |
| 折射率 | 1.5700 (estimate) |
| 酸度系数 | 4.08±0.20(Predicted) |
| 存储条件 | 2-8°C |
| 稳定性 | 稳定。与强氧化剂不相容。 |
| 敏感性 | Sensitive to light |
| 外观 | 粉末 |
| 颜色 | Dark red to maroon |
| BRN | 279110 |
| 物化性质 | 生物活性 Nile Red (Nile Blue A oxazone, Phenoxazone 9)是一种十分有效的荧光染料，可在疏水环境下检测细胞内脂质滴 intracellular lipid droplets。Nile Red 可用于细胞内脂质，蛋白质的疏水域和溶酶体磷脂内含体的染色。 |
| MDL号 | MFCD00011639 |
| 安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10 |
| 海关编号 | 29349990 |
| 上游原料 | 氢氧化钠 乙醚 醋酸 异丙醇 镍 1,4-萘醌 2-羟基-1,4-萘醌 |
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[IF=9.381] Yuxian Wang et al."Formulation of pH and temperature dual-responsive Pickering emulsion stabilized by chitosan-based microgel for recyclable biocatalysis."Carbohyd Polym. 2020 Aug;241:116373 25. [IF=9.147] Amr M. Bakry et al."Myofibrillar protein with κ- or λ-carrageenans as novel shell materials for microencapsulation of tuna oil through complex coacervation."Food Hydrocolloid. 2019 Nov;96:43 26. [IF=9.147] Xianling Wei et al."Fabrication and characterization of emulsions stabilized by tannic acid-wheat starch complexes."Food Hydrocolloid. 2020 Oct;107:105728 27. [IF=9.147] Shulin Zhang et al."Mixed plant-based emulsifiers inhibit the oxidation of proteins and lipids in walnut oil-in-water emulsions: Almond protein isolate-camellia saponin."Food Hydrocolloid. 2020 Dec;109:106136 28. 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[IF=6.953] Huaping Yu et al."Cellulose nanocrystals based clove oil Pickering emulsion for enhanced antibacterial activity."Int J Biol Macromol. 2021 Feb;170:24 42. [IF=5.875] Luyao Zheng et al."Novel skin permeation enhancers based on amino acid ester ionic liquid: Design and permeation mechanism."Int J Pharmaceut. 2020 Feb;576:119031 43. [IF=5.279] Xiaoying Zhang et al."Mechanism of Pentagalloyl Glucose in Alleviating Fat Accumulation in Caenorhabditis elegans."J Agr Food Chem. 2019;67(51):14110–14120 44. [IF=5.268] Long Xu et al."Polymeric nanoparticles responsive to intracellular ROS for anticancer drug delivery."Colloid Surface B. 2019 Sep;181:252 45. [IF=4.952] Ruihong Wang et al."Changes in egg yolk gelation behaviour and mechanisms during freezing."Lwt Food Sci Technol. 2021 Nov;151:112223 46. [IF=3.366] Huang Lu et al."Identification of Adulterated Extra Virgin Olive Oil by Colorimetric Sensor Array."Food Analytical Methods. 2021 Oct 31 47. 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尼罗红 - 性质
尼罗红是一种具有鲜艳红色的有机染料，化学名称为对二氨基偶氮苯硫酸钠。以下是尼罗红的一些性质：
1. 颜色和溶解度：尼罗红呈现鲜红色，是一种易溶于水的染料。
2. pH响应：尼罗红具有酸碱敏感性，其溶液的颜色会随着pH的变化而改变。在弱酸性条件下呈黄色，中性下呈红色，碱性条件下呈蓝色。
3. 稳定性：尼罗红对光、热和湿度相对稳定。但在强酸和强碱条件下，尼罗红可能会分解或变色。
4. 应用：尼罗红常用于生化实验中作为染料或者指示剂。它可以用于显微镜下观察细胞核和染色体的结构，也可以用于蛋白质凝胶电泳中的染色。
1. 颜色和溶解度：尼罗红呈现鲜红色，是一种易溶于水的染料。
2. pH响应：尼罗红具有酸碱敏感性，其溶液的颜色会随着pH的变化而改变。在弱酸性条件下呈黄色，中性下呈红色，碱性条件下呈蓝色。
3. 稳定性：尼罗红对光、热和湿度相对稳定。但在强酸和强碱条件下，尼罗红可能会分解或变色。
4. 应用：尼罗红常用于生化实验中作为染料或者指示剂。它可以用于显微镜下观察细胞核和染色体的结构，也可以用于蛋白质凝胶电泳中的染色。
最后更新：2024-04-10 22:29:15
尼罗红 - 用途与合成方法
尼罗红（Nile Red）是一种有机染料，常用于化学分析、生物荧光标记和材料科学研究中。以下是尼罗红的主要用途和合成方法的介绍：
用途：
1. 化学分析：尼罗红可用作指示剂和荧光探针，用于检测某些物质的存在、识别溶液中的离子和分析有机化合物。
2. 生物荧光标记：尼罗红具有很强的荧光特性，它被广泛用于生物荧光显微镜、流式细胞术和免疫组化技术等生物学研究中，用于标记和跟踪生物分子和细胞。
3. 材料科学研究：尼罗红可以作为染料、表面活性剂、光敏材料等应用于材料科学领域，例如超分子组装、液晶材料、电致变色等。
合成方法：
尼罗红的合成方法较为简单，其中一种常用的方法如下：
将苯胺与硝酸反应生成硝基苯胺（甲），然后用NaOH与邻硝基苯胺（甲）反应得到尼罗红。具体步骤如下：
1. 将苯胺加入含硫酸的冷混合酸中，与硝酸反应生成硝基苯胺（甲）。
2. 将硝基苯胺（甲）与过量的氢氧化钠反应，在碱性条件下形成尼罗红。
尼罗红的合成方法还有其他变种，但这是其中一种常用且较简便的方法。尼罗红的产率和纯度可以通过反应条件的调节来进行优化。
用途：
1. 化学分析：尼罗红可用作指示剂和荧光探针，用于检测某些物质的存在、识别溶液中的离子和分析有机化合物。
2. 生物荧光标记：尼罗红具有很强的荧光特性，它被广泛用于生物荧光显微镜、流式细胞术和免疫组化技术等生物学研究中，用于标记和跟踪生物分子和细胞。
3. 材料科学研究：尼罗红可以作为染料、表面活性剂、光敏材料等应用于材料科学领域，例如超分子组装、液晶材料、电致变色等。
合成方法：
尼罗红的合成方法较为简单，其中一种常用的方法如下：
将苯胺与硝酸反应生成硝基苯胺（甲），然后用NaOH与邻硝基苯胺（甲）反应得到尼罗红。具体步骤如下：
1. 将苯胺加入含硫酸的冷混合酸中，与硝酸反应生成硝基苯胺（甲）。
2. 将硝基苯胺（甲）与过量的氢氧化钠反应，在碱性条件下形成尼罗红。
尼罗红的合成方法还有其他变种，但这是其中一种常用且较简便的方法。尼罗红的产率和纯度可以通过反应条件的调节来进行优化。
最后更新：2024-04-10 22:29:15
供应商列表
现货供应
产品名: NileRed尼罗红 去供应商网站查看 询盘CAS: 7385-67-3
产地: 北京
包装: 瓶
规格: N8440-100mg,100mg,IN0170-D-1ml,10mM*1ml(inDMSO),IN0170-5mg,5mg,IN0170-10mg,10mg,IN0171-5mg,5mg,IN017
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库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
现货供应
产品名: NileRed尼罗红 去供应商网站查看 询盘CAS: 7385-67-3
产地: 北京
包装: 瓶
规格: N8440-100mg,100mg,IN0170-D-1ml,10mM*1ml(inDMSO),IN0170-5mg,5mg,IN0170-10mg,10mg,IN0171-5mg,5mg,IN017
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
尼罗红的上游原料
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