杨梅苷含一个结晶水晶体的熔点为194~197℃。
黑杨梅的果实、树皮和叶子用水、乙醇或甲醇提取后,再精制而得。
可用作抗氧化剂。添加到化妆品中,具有美白皮肤的作用。
中文名 | 杨梅苷 |
英文名 | 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-one |
别名 | 杨梅甙 楊梅苷 大麻苷 杨梅苷 杨梅树皮苷 大麻黃酮苷 杨梅树皮提取物 五羟基黄酮-3-鼠李糖苷 杨梅苷.杨梅甙.杨梅树皮甙 |
英文别名 | MYRICITRIN myricitrin 17912-87-7 Myricetrin CANNABISCITRIN MYRICETIN-3-RHAMNOSIDE MYRICETIN-3-O-RHAMNOSIDE MYRICETIN-3-O-RHAVINOSIDE 5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl 6-deoxyhexopyranoside 5,7-Dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl 6-deoxy-a-L-mannopyranoside 5,7-Dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl-6-deoxy-alpha-L-mannopyranoside 5,7-Dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-one 6-Désoxy-alpha-L-mannopyranoside de 5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphényl)-4H-chromén-3-yle 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-one 4H-1-benzopyran-4-one, 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)- 5,7-dihydroxy-3-((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-(3,4,5-trihydroxy-phenyl)-1-benzopyran-4-one 5,7-Dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-on 5,7-Dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}-2-(3,4,5-trihydroxyphényl)-4H-chromén-4-one 5,7-Dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one |
CAS | 17912-87-7 |
EINECS | 241-856-7 |
化学式 | C21H20O12 |
分子量 | 464.38 |
InChI | InChI=1/C21H20O12/c1-6-14(26)17(29)18(30)21(31-6)33-20-16(28)13-9(23)4-8(22)5-12(13)32-19(20)7-2-10(24)15(27)11(25)3-7/h2-6,14,17-18,21-27,29-30H,1H3 |
密度 | 1.88±0.1 g/cm3(Predicted) |
熔点 | 197°C(lit.) |
沸点 | 896.6±65.0 °C(Predicted) |
比旋光度 | -138.6 (c, 0.5 in MeOH) |
闪点 | 315.6°C |
蒸汽压 | 1.44E-34mmHg at 25°C |
JECFA Number | 2207 |
溶解度 | 溶于DMSO、热甲醇,微溶溶于水和无水乙醇。 |
折射率 | 1.805 |
酸度系数 | 6.16±0.40(Predicted) |
存储条件 | -20°C |
外观 | 整洁 |
颜色 | Light yellow to Yellow to Orange |
物化性质 | 黄色结晶粉末,易溶于水,能溶于甲醇、乙醇、冰乙酸,来源于萹蓄,杨梅树皮,杨梅叶。 |
MDL号 | MFCD00016930 |
体外研究 | Myricitrin,一个从蜡果杨梅根皮中分离出的化合物,能够发挥镇痛作用。啮齿动物的化学和机械疼痛模型中,Myricitrin通过阻止蛋白激酶C (PKC) α和PKCε被佛波酯(PMA)激活而产生明显的镇痛作用。 另一项研究证明电压和小电导钙门控K(+)通道的开放以及钙离子内流的减少是myricitrin产生镇痛作用的原因。Myricitrin也会通过抑制p53基因的表达,激活胱天蛋白酶-3和MAPK信号通路,并且改变促凋亡和抗凋亡基因表达的模式而减少血管内皮细胞中H 2 O 2 诱导的细胞凋亡。 |
体内研究 | 在小鼠体内,myricitrin (i.p. 10 mg/kg 或30 mg/kg)阻断阿扑吗啡诱导的刻板行为和攀登,并增加后肢撤回时间(HRT)。 |
安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
海关编号 | 29389090 |
下游产品 | 杨梅素 |
参考资料 展开查看 | 1. 郭双双 郑芳芳 可丛雪 等. 乳酸片球菌AS1.2696来源的α-L-鼠李糖苷酶酶学性质分析[J]. 食品科学 2019 040(004):160-169. 2. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254 3. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56 4. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro 5. [IF=4.879] Yang Liu et al."UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings."Biomolecules. 2020 Apr;10(4):504 6. [IF=4.411] Min Yang et al."Comparative Transcriptome Analysis of Ampelopsis megalophylla for Identifying Genes Involved in Flavonoid Biosynthesis and Accumulation during Different Seasons."Molecules. 2019 Jan;24(7):1267 7. [IF=4.36] Zhao-Yi Wang et al."Integrated strategy of LC-MS and network pharmacology for predicting active constituents and pharmacological mechanisms of Ranunculus japonicus Thunb. for treating rheumatoid arthritis."J Ethnopharmacol. 2021 May;271:113818 8. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 |
杨梅苷含一个结晶水晶体的熔点为194~197℃。
黑杨梅的果实、树皮和叶子用水、乙醇或甲醇提取后,再精制而得。
可用作抗氧化剂。添加到化妆品中,具有美白皮肤的作用。
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