脱氧可的松_化工百科

中文名	皮甾酮
英文名	Cortexolone
别名	皮甾酮可托多松脱氧可的松
英文别名	Cortifen SKF 3050 Compound S Cortodoxone Cortexolone Reichstein S 11-Dioxycortisol 11-Deoxycortisol cortodoxone (INN) 11-Desoxycortisol 11-Deoxycortisone 11-Desoxycortisone Cortisol, 11-dioxy- Cortisol, 11-deoxy- 17α-Hydroxycortexone 17a-Hydroxycortexone 11-Deoxyhydrocortisone 11-Desoxyhydrocortisone Reichstein's Substanz S Reichstein's compound S Reichstein's substance S 17,21-Dihydroxyprogesterone 17α,21-Dihydroxyprogesterone 17a,21-Dihydroxyprogesterone 4-Pregnen-17a,21-diol-3,20-dion 4-Pregnen-17α,21-diol-3,20-dion 11-Deoxy-17-hydrocorticosterone 17-Hydroxy-11-deoxycorticosterone 11-Deoxy-17-hydroxycorticosterone 4-Pregnene-17α, 21-diol-3,20-dione 11-Desoxy-17-hydroxycorticosterone 4-Pregnene-17a, 21-diol-3,20-dione 11-Desoxy-17a-hydroxycorticosterone 11-Desoxy-17α-hydroxycorticosterone Corticosterone, 11-deoxy-17-hydroxy- 17a,21-Dihydroxy-4-pregnen-3,20-dion 17α,21-Dihydroxy-4-pregnen-3,20-dion 17,21-Dihydroxypregn-4-ene-3,20-dione 17,21-Dihydroxy-4-pregnene-3,20-dione 17,21-dihydroxy-pregn-4-ene-3,20-dione 17a,21-dihydroxypregn-4-ene-3,20-dione 17α,21-dihydroxypregn-4-ene-3,20-dione Pregn-4-ene-3,20-dione, 17,21-dihydroxy- PCB NO.101-2,2',4,5,5'-PENTACHLOROBIPHENYL 17alpha,21-Dihydroxypregn-4-ene-3,20-dione (8xi,9xi,10xi,13xi,14xi)-17,21-dihydroxypregn-4-ene-3,20-dione (8R,10R,13S,17R)-17-Hydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
CAS	152-58-9 37-60-5
EINECS	205-805-2
化学式	C21H30O4
分子量	346.4605
InChI	InChI=1/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1
密度	1.22g/cm³
熔点	205-208℃
沸点	524.5°C at 760 mmHg
闪点	285.1°C
蒸汽压	3.41E-13mmHg at 25°C
溶解度	溶于丙酮、甲醇和乙醇，极微溶于水和乙醚
折射率	1.577
存储条件	2-8℃
敏感性	Sensitive to air
外观	结晶固体
MDL号	MFCD00003662
安全术语	S24/25 - 避免与皮肤和眼睛接触。
参考资料展开查看	1. Chen, Jing, et al. "Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone." Metabolic engineering 57 (2020): 31-42.https://do 2. [IF=9.783] Jing Chen et al."Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone."Metab Eng. 2020 Jan;57:31

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