中文名 | 1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐 |
英文名 | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride |
别名 | EDC盐酸盐 1-乙基-3-(3-二甲基銨丙基)碳銨 1-(3-二甲氨基丙基)乙基碳二亚胺盐酸盐 乙基-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 1-(3-二甲胺丙基)-3-乙基碳二亚胺盐酸盐 1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐 1-乙基-3-(3-二甲氨丙基)碳二亚胺盐酸盐 1-乙基-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐 1-(3-二甲氨基丙基)-3-乙基-碳二亚胺盐酸盐 N-(3-二甲氨基丙基)-N'-乙基-碳二亚胺盐酸盐 1-乙基-3-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐 1-(3-二甲基氨基丙基)-3-乙基碳化二亚胺盐酸盐 1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐(EDCI) |
英文别名 | WSC EDC·HCl EDC.HCL EDC.HCI EDC HCL EDC.HCl EDAC HCL EDAC.HCL EDAC,HCl EDC (WSC-HCl) AT test ,only COA Avanafil Impurity 40 Diquafosol Impurity m 1-[3-Dimethylamino propyl]-3-ethyl carbodiimide Hcl 3-ethylazo-N,N-dimethyl-propan-1-amine hydrochloride 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydroc (3-dimethylaminopropyl)ethyl-carbodiimidmonohydrochloride N-Ethyl-N-(3-dimethylaminopropyl)carbodiimide hydrochloride 3-[cyano(ethyl)amino]-N,N-dimethylpropan-1-aminium chloride N-(3-Dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide hydrochloride 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide Hydrochloride 1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride N-(3-Dimethylaminopropyl)-N'-Ethylcarbodiimide Hydrochloride 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride 3-propanediamine,n'-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride 3-propanediamine,n'-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride N'-(Ethylkohlenstoffimidoyl)-N,N-dimethylpropan-1,3-diaminmonohydrochlorid |
CAS | 25952-53-8 |
EINECS | 247-361-2 |
化学式 | C8H18ClN3 |
分子量 | 191.7 |
InChI | InChI=1/C7H17N3.ClH/c1-4-8-9-6-5-7-10(2)3;/h4-7H2,1-3H3;1H/b9-8+ |
InChIKey | FPQQSJJWHUJYPU-UHFFFAOYSA-N |
密度 | 0.877g/mLat 20°C(lit.) |
熔点 | 110-115°C(lit.) |
沸点 | 209.2°C at 760 mmHg |
闪点 | 80.3°C |
水溶性 | Soluble |
蒸汽压 | 0.002Pa at 20℃ |
溶解度 | H2O: 溶解1 gm/10毫升,澄清至非常模糊,无色至非常微弱的黄色 |
折射率 | n20/D 1.461 |
存储条件 | -20°C |
稳定性 | 稳定,但对水分敏感。与强酸、强氧化剂、湿气不相容。 |
敏感性 | Hygroscopic |
外观 | 结晶性粉末 |
颜色 | White to off-white |
BRN | 5764110 |
物化性质 | 白色结晶。熔点111-113℃。 |
MDL号 | MFCD00012503 |
危险品标志 | C - 腐蚀性物品 Xi - 刺激性物品 |
风险术语 | R34 - 引起灼伤。 R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 R41 - 对眼睛有严重伤害。 R37/38 - 刺激呼吸系统和皮肤+B52。 R20/21/22 - 吸入、皮肤接触及吞食有害。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 S37/39 - 戴适当的手套和护目镜或面具。 S36 - 穿戴适当的防护服。 |
危险品运输编号 | UN 2735 8/PG 3 |
WGK Germany | 3 |
RTECS | FF2200000 |
FLUKA BRAND F CODES | 1-3-10 |
TSCA | Y |
海关编号 | 29252000 |
Hazard Note | Irritant |
上游原料 | 3-((二甲基氨基)苯基硫代异氰酸酯 N,N-二甲基-1,3-二氨基丙烷 |
下游产品 | 6-溴-4-氯-2-甲基喹唑啉 6-溴-2-甲基喹唑啉-4(3H)-酮 1-甲基环丙烷磺酰胺 |
参考资料 展开查看 | 1. 魏锁成 巩转娣 董江陵 谢坤 李琼毅 韦敏.Alarelin免疫绵羊对垂体GnRHR、FSHR和LHR基因表达与生殖激素分泌的作用[J].基础医学与临床 2012 32(10):1137-1142. 2. 陈卓 石蕊 谭李玉 等. DHA-丝裂霉素C偶联前药的制备及角膜透过性研究[J]. 中国油脂 2017(8). 3. 巩转娣 魏锁成 韦敏 等. GnRHa主动免疫对幼鼠子宫发育的作用[J]. 免疫学杂志 2011(12):1067-1070. 4. 魏锁成 巩转娣 欧阳霞辉 等. GnRH激动剂主动免疫母羊对生殖激素分泌的作用[J]. 中国免疫学杂志 2012 28(2):132-136. 5. 陈卓 石蕊 谭李玉 等. 低分子量聚谷氨酸的制备及其在眼科靶向药物中的应用研究[J]. 当代化工 2016(12):2787-2789. 6. 赵雪竹 刘洋 王艳萍 刘福强 张琦 刘丹 赵楠 韩丹 赵庆兰.原料纯度对白及多糖疏水改性反应取代度的影响[J].药学实践杂志 2015 33(03):221-225. 7. 贾谊君 林清 王传英 等. 叶酸修饰稀土改性载氧碳纳米管增加乳腺癌细胞株放疗敏感性的体外实验初步研究[J]. 现代生物医学进展 2014 14(022):4205-4209. 8. 孔凡娇, 万金泉, 马邕文,等. 改性漆酶协同谷氨酸改善二次纤维微观结构及性能的研究[J]. 中国造纸, 2017, 36(004):1-6. 9. 尹苗, 徐飞, 丁慧芬,等. 正电荷修饰对光交联海藻酸盐水凝胶支架细胞粘附性能的影响[J]. 口腔医学研究, 2014(3):205-208. 10. 侯红萍, 张萍, 王如福. 生物素-亲和素系统定向固定糖化酶的研究[J]. 中国食品学报, 2014, 14(003):106-114. 11. 高先娟, 汲霞, 王清路,等. 羧基化石墨烯/半胱胺修饰金电极对多巴胺的电化学行为研究[J]. 生物技术进展, 2020, v.10;No.57(03):82-88. 12. 魏锁成, 陈鲁杰, 巩转娣. 西曲瑞克和曲普瑞林对小鼠免疫效应的对比实验研究[J]. 免疫学杂志, 2015(07):585-590. 13. 王新, 铁朝荣, 尹苗,等. 铜离子光双交联海藻酸盐水凝胶支架材料的性能研究[J]. 临床口腔医学杂志, 2020, 036(002):84-88. 14. 杨琳燕,王笑,宗云鹤,扈立伟,臧莲娜,艾霞,李存,金天明.基于γ-Fe_2O_3磁性纳米微球的MSPE研究[J].南开大学学报(自然科学版),2018,51(01):101-105. 15. 刘天娇, 刘福强, 王艳萍,等. 白及多糖疏水改性的研究[J]. 中成药, 2015, 37(002):423-426. 16. 汤玉娇, 戴诗岩, 周羽婷,等. 基于DNA模板点击化学和催化发夹型DNA自组装反应的新型均相电化学生物传感器检测miRNA-21[J]. 分析化学, 2019(7):1029-1034. 17. 沙青,李贺,张红,程博群,王莹,闫琳琳,邹馨颖,张志民.EDC对牙本质即刻及老化微拉伸粘接强度的影响[J].吉林大学学报(医学版),2021,47(01):173-179. 18. 辛亮亮,舒玥,刘欢,胡雅稳,杨琳燕.PEG修饰Fe_3O_4纳米粒子(MNPs)的制备及载药研究[J].天津农学院学报,2020,27(03):43-48. 19. Sun, Xiuhua, et al. "Creation of antifouling microarrays by photopolymerization of zwitterionic compounds for protein assay and cell patterning." Biosensors and Bioelectronics 102 (2018): 63-69.https://doi.org/10.1016/j.bios.2017.11.001 20. Zhao, Delu, et al. "Effect of altering photocrosslinking conditions on the physical properties of alginate gels and the survival of photoencapsulated cells." Polymer Degradation and Stability 179 (2020): 109297.https://doi.org/10.1016/j.polymdegradstab.202 21. Lin, Zefeng, et al. "Biofunctions of antimicrobial peptide-conjugated alginate/hyaluronic acid/collagen wound dressings promote wound healing of a mixed-bacteria-infected wound." International journal of biological macromolecules 140 (2019): 330-342.https: 22. Zhou, Mou, et al. "Development of nanosilver doped carboxymethyl chitosan-polyamideamine alginate composite dressing for wound treatment." International Journal of Biological Macromolecules 166 (2021): 1335-1351.https://doi.org/10.1016/j.ijbiomac.2020.11.0 23. Wang Y, Lin FX, Zhao Y, et al. The sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles. Int J Nanomedicine. 2014;9:4965-4978. Published 2014 Oct 23. https://doi.org/10.21 24. Wang, Xueqing, et al. "Silica-Coated Silver Nanoparticles Decorated with Fluorescent CdTe Quantum Dots and DNA Aptamers for Detection of Tetracycline." ACS Applied Nano Materials 3.10 (2020): 9796-9803.https://doi.org/10.1021/acsanm.0c01890 25. Cheng, Y., Zhang, S., Li, J., Sun, J., Wang, J., Qin, C., & Dai, L. (2017). Preparation of functionalized partially unzipped carbon nanotube/polyimide composite fibers with increased mechanical and thermal properties. RSC advances, 7, 21953-21961. doi: 10. 26. Li Y, Zhang L, Shi Y, Huang J, Yang Y, Ming D. Poly(N-Isopropylacrylamide)-Functional Silicon Nanocrystals for Thermosensitive Fluorescence Cellar Imaging. Polymers. 2020; 12(11):2565. https://doi.org/10.3390/polym12112565 27. Liu, Qiurui, et al. "Development of direct competitive biomimetic immunosorbent assay based on quantum dot label for determination of trichlorfon residues in vegetables." Food chemistry 250 (2018): 134-139.https://doi.org/10.1016/j.foodchem.2017.12.079 28. Wang, Jing, et al. "cRGDyK-modified camretastain A4-loaded graphene oxide nanosheets for targeted anticancer drug delivery." RSC advances 5.50 (2015): 40258-40268.10.1039/C4RA17240J 29. Lin, Fu-xing, et al. "Chitosan-based core–shell structured particles for in vivo sustainable gene transfection." Journal of Materials Chemistry B 4.5 (2016): 893-901.https://doi.org/10.1039/C5TB02074C 30. Feilong Yan, Qifeng Dang, Chengsheng Liu, Jingquan Yan, Teng Wang, Bing Fan, Dongsu Cha, Xiaoli Li, Shengnan Liang, Zhenzhen Zhang, 3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism, Carbohydrate Po 31. Liang, Ying, et al. "A label-free immunosensor based on PHEMA/graphene oxide nanocomposite for simultaneous electrochemical determination of alpha fetoprotein." RSC advances 9.30 (2019): 17187-17193. 32. Zhang, Haichao, et al. "Deterministic Lateral Displacement-Based Separation of Magnetic Beads and Its Applications of Antibody Recognition." Sensors 20.10 (2020): 2846.https://doi.org/10.3390/s20102846 33. Cheng, Dan, et al. "An electrochemical DNA sensing platform using carboxyl functionalized graphene as the electrode modified material." Journal of The Electrochemical Society 164.6 (2017): H345. 34. Cheng, Dan, et al. "A non-enzymatic electrochemical sensing platform based on hemin@ MOF composites for detecting hydrogen peroxide and DNA." Journal of The Electrochemical Society 165.16 (2018): B885. 35. Chen, Yangmei, et al. "Chemical modification of laccase from Aspergillus oryzae and its application in OCC pulp." BioResources 12.1 (2017): 673-683. 36. Chen, S., Li, Y., Wu, S. et al. A phosphorescent probe for cephalexin consisting of mesoporous thioglycolic acid-modified Mn:ZnS quantum dots coated with a molecularly imprinted polymer. Microchim Acta 187, 40 (2020). https://doi.org/10.1007/s00604-019-403 37. [IF=10.618] Xiuhua Sun et al."Creation of antifouling microarrays by photopolymerization of zwitterionic compounds for protein assay and cell patterning."Biosens Bioelectron. 2018 Apr;102:63 38. [IF=9.381] Feilong Yan et al."3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism."Carbohyd Polym. 2016 Sep;149:102 39. [IF=7.514] Qiurui Liu et al."Development of direct competitive biomimetic immunosorbent assay based on quantum dot label for determination of trichlorfon residues in vegetables."Food Chem. 2018 Jun;250:134 40. [IF=6.4] Yun Wang et al."The sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles."Int J Nanomed. 2014; 9: 4965–4978 41. [IF=6.4] Yishun Yang et al."Reduction-sensitive CD44 receptor-targeted hyaluronic acid derivative micelles for doxorubicin delivery."Int J Nanomed. 2018; 13: 4361–4378 42. [IF=5.251] Aipeng Deng et al."Electrospinning of in situ crosslinked recombinant human collagen peptide/chitosan nanofibers for wound healing."Biomater Sci-Uk. 2018 Jul;6(8):2197-2208 43. [IF=5.162] Shengxue Hu et al."Preparation of biocompatible wound dressings with long-term antimicrobial activity through covalent bonding of antibiotic agents to natural polymers."Int J Biol Macromol. 2019 Feb;123:1320 44. [IF=4.316] Dan Cheng et al."A Non-Enzymatic Electrochemical Sensing Platform Based on Hemin@MOF Composites for Detecting Hydrogen Peroxide and DNA."J Electrochem Soc. 2018 Dec;165(16):B885 45. [IF=4.142] He Baoshan et al."Novel electrochemical aptasensor for ultrasensitive detection of sulfadimidine based on covalently linked multi-walled carbon nanotubes and in situ synthesized gold nanoparticle composites."Anal Bioanal Chem. 2018 May;410(12):2901-2910 46. [IF=4.094] Yating Wang et al."Synthesis of PGMA/AuNPs amplification platform for the facile detection of tumor markers."Mater Chem Phys. 2016 Nov;183:534 47. [IF=3.049] Jing Wang et al."cRGDyK-modified camretastain A4-loaded graphene oxide nanosheets for targeted anticancer drug delivery."Rsc Adv. 2015 Apr;5(50):40258-40268 48. [IF=3.049] Qingqing Tian et al."Targeted solid lipid nanoparticles with peptide ligand for oral delivery of atorvastatin calcium."Rsc Adv. 2016 Apr;6(42):35901-35909 49. [IF=2.896] Linlin Yang et al."Single-walled carbon nanotubes–carboxyl-functionalized graphene oxide-based electrochemical DNA biosensor for thermolabile hemolysin gene detection."Anal Methods-Uk. 2015 Jun;7(12):5303-5310 50. [IF=2.896] Jing Wang et al."Electrochemical immunosensor detection of tumor markers based on a GO composite nanoprobe for signal amplification."Anal Methods-Uk. 2018 Feb;10(5):526-532 51. [IF=2.896] Bao-Shan He et al."Electrochemical aptasensor based on aptamer-complimentary strand conjugate and thionine for sensitive detection of tetracycline with multi-walled carbon nanotubes and gold nanoparticles amplification."Anal Methods-Uk. 2018 Feb;10(7):783 52. [IF=2.896] Dongcheng Yang et al."An efficient method for the synthesis of a polymer brush via click chemistry and its ultrasensitive electrochemical detection of AFP."Anal Methods-Uk. 2018 May;10(20):2390-2397 53. [IF=18.808] Xiangyi Yin et al."Bio-Multifunctional Hydrogel Patches for Repairing Full-Thickness Abdominal Wall Defects."Adv Funct Mater. 2021 Oct;31(41):2105614 54. [IF=13.273] Shengyu Bai et al."Chemical reaction powered transient polymer hydrogels for controlled formation and free release of pharmaceutical crystals."Chem Eng J. 2021 Jun;414:128877 55. [IF=10.435] Qiang Lei et al."A novel macrophage-mediated biomimetic delivery system with NIR-triggered release for prostate cancer therapy."J Nanobiotechnol. 2019 Dec;17(1):1-15 56. [IF=7.79] Songbo Zhao et al."Surface specifically modified NK-92 cells with CD56 antibody conjugated superparamagnetic Fe3O4 nanoparticles for magnetic targeting immunotherapy of solid tumors."Nanoscale. 2021 Oct;: 57. [IF=7.79] Zhigang Fang et al."Sgc8 aptamer targeted glutathione-responsive nanoassemblies containing Ara-C prodrug for the treatment of acute lymphoblastic leukemia."Nanoscale. 2019 Dec;11(47):23000-23012 58. [IF=7.711] Rong Zhang et al."A Disposable Printed Liquid Gate Graphene Field Effect Transistor for a Salivary Cortisol Test."Acs Sensors. 2021;6(8):3024–3031 59. [IF=7.514] Shiqi Li et al."Smartphone-based reading system integrated with phycocyanin-enhanced latex nanospheres immunoassay for on-site determination of aflatoxin B1 in foodstuffs."Food Chem. 2021 Oct;360:130019 60. [IF=7.46] Shengyong Ding et al."A strand-elongation initiated DNAzyme walker for terminal deoxynucleotidyl transferase activity detection."Sensor Actuat B-Chem. 2021 Oct;344:130204 61. [IF=6.953] Zhang Man et al."An in situ catechol functionalized ε-polylysine/polyacrylamide hydrogel formed by hydrogen bonding recombination with high mechanical property for hemostasis."Int J Biol Macromol. 2021 Nov;191:714 62. [IF=6.953] Linglan Yang et al."Promote anti-inflammatory and angiogenesis using a hyaluronic acid-based hydrogel with miRNA-laden nanoparticles for chronic diabetic wound treatment."Int J Biol Macromol. 2021 Jan;166:166 63. [IF=6.953] Sidi Li et al."Metal-crosslinked ɛ-poly-L-lysine tissue adhesives with high adhesive performance: Inspiration from mussel adhesive environment."Int J Biol Macromol. 2020 Jun;153:1251 64. [IF=5.645] Ru Zhao et al."Biodiesel preparation from Thlaspi arvense L. seed oil utilizing a novel ionic liquid core-shell magnetic catalyst."Ind Crop Prod. 2021 Apr;162:113316 65. [IF=5.443] Wei Jie et al."Evaluation of Silk Fibroin-RGD-Stem Cell Factor Scaffold Effect on Adhesion, Migration, and Proliferation of Stem Cells of Apical Papilla."Stem Cells Int. 2021;2021:6612324 66. [IF=5.162] Zefeng Lin et al."Biofunctions of antimicrobial peptide-conjugated alginate/hyaluronic acid/collagen wound dressings promote wound healing of a mixed-bacteria-infected wound."Int J Biol Macromol. 2019 Nov;140:330 67. [IF=5.162] Mou Zhou et al."Development of nanosilver doped carboxymethyl chitosan-polyamideamine alginate composite dressing for wound treatment."Int J Biol Macromol. 2021 Jan;166:1335 68. [IF=4.952] Yanan Xu et al."Assembly of zein–polyphenol conjugates via carbodiimide method: Evaluation of physicochemical and functional properties."Lwt Food Sci Technol. 2022 Jan;154:112708 69. [IF=4.821] Xueqing Wang et al."Surface plasma enhanced fluorescence combined aptamer sensor based on silica modified silver nanoparticles for signal amplification detection of cholic acid."Microchem J. 2021 Sep;168:106524 70. [IF=4.749] Jimin Sun et al."Transglutaminase-Catalyzed Encapsulation of Individual Mammalian Cells with Biocompatible and Cytoprotective Gelatin Nanoshells."Acs Biomater Sci Eng. 2020;6(4):2336–2345 71. [IF=4.539] Dong-xue Ren et al."pH/redox dual response nanoparticles with poly-γ-glutamic acid for enhanced intracellular drug delivery."Colloid Surface A. 2019 Sep;577:412 72. [IF=4.367] Sidi Li et al."Environment-Dependent Adhesive Behaviors of Mussel-Inspired Coordinate-Crosslinked Bioadhesives."Macromol Mater Eng. 2020 Jan;305(1):1900620 73. [IF=4.329] Yiting Li et al."Poly(N-Isopropylacrylamide)-Functional Silicon Nanocrystals for Thermosensitive Fluorescence Cellar Imaging."Polymers-Basel. 2020 Nov;12(11):2565 74. [IF=4.24] Hongsu Wang et al."Composite chitosan films prepared using nisin and Perilla frutescense essential oil and their use to extend strawberry shelf life."Food Biosci. 2021 Jun;41:101037 75. [IF=4.098] Shujuan Chen et al."A magnetic phosphorescence molecularly imprinted polymers probe based on manganese-doped ZnS quantum dots for rapid detection of trace norfloxacin residual in food."Spectrochim Acta A. 2021 May;253:119577 76. [IF=4.098] Ai-Yue Hao et al."A smartphone-combined ratiometric fluorescence probe for specifically and visibly detecting cephalexin."Spectrochim Acta A. 2021 Mar;249:119310 77. [IF=3.978] Jingyang Zhao et al."Self-assembled pH-responsive polymeric nanoparticles based on lignin-histidine conjugate with small particle size for efficient delivery of anti-tumor drugs."Biochem Eng J. 2020 Apr;156:107526 78. [IF=3.644] Wang Xinlu et al."Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing."Front Bioeng Biotech. 2019 Dec;0:360 79. [IF=3.517] Fangfang Xie et al."Effect of a new modified polyamidoamine dendrimer biomimetic system on the mineralization of type I collagen fibrils: an in vitro study."Journal Of Biomaterials Science-Polymer Edition. 2021 Oct 03 80. [IF=3.361] Ying Liang et al."A label-free immunosensor based on PHEMA/graphene oxide nanocomposite for simultaneous electrochemical determination of alpha fetoprotein."Rsc Adv. 2019 May;9(30):17187-17193 81. [IF=3.275] Haichao Zhang et al."Deterministic Lateral Displacement-Based Separation of Magnetic Beads and Its Applications of Antibody Recognition."Sensors-Basel. 2020 Jan;20(10):2846 82. [IF=3.266] Zhengsong Yu et al."Highly efficient electrochemical detection of lead ion using metal-organic framework and graphene as platform based on DNAzyme."Synthetic Met. 2019 Aug;254:164 83. [IF=3.101] Ximo Wang et al."Development of molecularly imprinted biomimetic immunoassay method based on quantum dot marker for detection of phthalates."Food Agr Immunol. 2019;30(1):1007-1019 84. [IF=2.896] Na Wang et al."Facile fabrication of a controlled polymer brush-type functional nanoprobe for highly sensitive determination of alpha fetoprotein."Anal Methods-Uk. 2020 Sep;12(36):4438-4446 85. [IF=1.967] Min Wei et al."A novel signal-on fluorescent aptasensor for ochratoxin A detection based on RecJf exonuclease-induced signal amplification."J Chin Chem Soc-Taip. 2020 Jul;67(7):1247-1253 86. [IF=1.415] R. Zhang et al."Total solution processable and low-cost DNA methylation sensor."J Instrum. 2021 Sep;16(09):P09021 87. [IF=4.329] Thi My Do et al.Porous Bilayer Vascular Grafts Fabricated from Electrospinning of the Recombinant Human Collagen (RHC) Peptide-Based Blend.Polymers-Basel. 2021 Jan;13(22):4042 88. [IF=9.381] Yuanping Hao et al."Carboxymethyl chitosan-based hydrogels containing fibroblast growth factors for triggering diabetic wound healing."Carbohyd Polym. 2022 Jul;287:119336 89. [IF=4.142] Luo Dajuan et al."Signal-on photoelectrochemical immunoassay for salivary cortisol based on silver nanoclusters-triggered ion-exchange reaction with CdS quantum dots."Anal Bioanal Chem. 2022 Feb;:1-10 90. [IF=2.647] Luo Dajuan et al."TiO2/CuInS2-sensitized structure for sensitive photoelectrochemical immunoassay of cortisol in saliva."J Solid State Electr. 2022 Mar;26(3):749-759 91. [IF=3.846] Xin Tian et al."The properties of cholesterol-modified pullulan nanoparticles with different PEG coatings and their anti-hepatoblastoma cell effects."Materials Technology. 2022 Jan 23 92. [IF=4.821] Weidao Yu et al."A turn-on fluorescent aptasensor for ampicillin detection based on gold nanoparticles and CdTe QDs."Microchem J. 2022 Aug;179:107454 |
1-乙基-(3-二甲基氨基丙基)碳二亚胺盐酸盐,又称为EDC盐酸盐。以下是对其性质、用途、制法和安全信息的介绍:
性质:
1、EDC盐酸盐是一种白色结晶粉末,具有弱酸性。
2、它在水中易溶,在有机溶剂如醇、醚等中也溶解性良好。
3、EDC盐酸盐在室温下稳定。
用途:
1、EDC盐酸盐是一种常用的化学反应剂,在有机合成中具有广泛的应用。
2、作为活化剂:EDC盐酸盐可以与氨基酸或肽键发生反应,生成酰基化中间体,从而在肽合成和蛋白质修饰等领域中发挥重要作用。
3、作为偶联剂:EDC盐酸盐可以将酸和醇偶联形成酯键,用于合成酯化物、醚类和酰亚胺等化合物。
4、用于染料和颜料的合成。
制法:
EDC盐酸盐可以通过将EDC与盐酸反应得到。具体操作时,将EDC与足量的盐酸溶液混合,搅拌并加热反应,最后蒸发溶剂得到EDC盐酸盐的结晶。
安全信息:
1、EDC盐酸盐可能对皮肤、眼睛和呼吸道有刺激作用,应戴好防护手套、护目镜和口罩。
2、避免直接吸入或接触EDC盐酸盐的粉末。
3、在使用EDC盐酸盐时,应注意室内通风良好,避免吸入其挥发的气体。
4、在处理EDC盐酸盐时,应小心防止其被吞食或误食。
5、应存放在干燥、远离热源的地方,避免与氧化剂和易燃物接触。
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