102120-99-0_化工百科

中文名	rac-Rotigotine Hydrochloride
英文名	rac-Rotigotine Hydrochloride
别名	消旋罗替戈汀盐酸罗替高汀罗替高汀消旋体罗替高汀-D7盐酸化合物 T12676 5,6,7,8-四氢-6-[丙基[2-(2-噻吩基)乙基]氨基]-1-萘酚盐酸盐
英文别名	Rotigotine-d7 HCl N 0437 hydrochloride rac-Rotigotine Hydrochloride 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-1-naphthalenol Hydrochloride 1-Naphthalenol,5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-,hydrochloride
CAS	102120-99-0
化学式	C19H26ClNOS
分子量	351.93384
熔点	>118°C (dec.)
溶解度	丙酮，DMSO，甲醇
存储条件	Refrigerator
外观	固体
颜色	White to Off-White
体外研究	Rotigotine has a 10-fold selectivity for D3 (pK i =9.2) receptors compared with D2, D4 and D5 (pK i =8.5-8.0) and a 100-fold selectivity compared with D1 receptors (pK i =7.2). In functional studies, Rotigotine behaves as full agonist at all dopamine receptors but notably the potency for stimulation of D1 receptors is similar to that for D2 and D3 receptors (pEC 50 respectively: 9.0, 9.4-8.6, 9.7). Rotigotine (10 µM) decreases the number of THir neurons by 40% in primary mesencephalic cell culture. Rotigotine (0.01 µM) slightly protects dopaminergic neurons against MPP+toxicity, significantly protects dopaminergic neurons against rotenone-induced cell death, and significantly inhibits ROS production by rotenone. .
海关编号	2934990002

102120-99-0 - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	2.841 ml	14.207 ml	28.415 ml
5 mM	0.568 ml	2.841 ml	5.683 ml
10 mM	0.284 ml	1.421 ml	2.841 ml
5 mM	0.057 ml	0.284 ml	0.568 ml

最后更新：2024-01-02 23:10:35

湖北扬信医药科技有限公司

现货供应

产品名: 罗替戈汀杂质2(盐酸罗替戈汀消旋体) 去供应商网站查看询盘
CAS: 102120-99-0
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
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上海吉至生化科技有限公司

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产品名: (Rac)-Rotigotine hydrochloride 去供应商网站查看询盘
CAS: 102120-99-0
产地: 中国上海
包装: 50mg
规格: 97%
价格: 2128.00
库存: 现货
电话: 400-900-4166
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产品描述: 中文名：(Rac)-Rotigotine hydrochloride 英文名:rac-Rotigotine Hydrochloride CAS:102120-9 更多

上海麦克林生化科技股份有限公司

现货供应

产品名: (Rac)-Rotigotine hydrochloride 去供应商网站查看询盘
CAS: 102120-99-0
产地: 上海
规格: R884909
价格: 50mg-1758,10mg-608
库存: 现货
电话: 13816333479/13918391375
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上海源叶生物科技有限公司

产品名: rac-Rotigotine Hydrochloride 去供应商网站查看询盘
CAS: 102120-99-0
产地: 上海
规格: 97%
价格: 10mg 818,50mg 2046,100mg 3050
电话: 18301782025
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