中文名 | 桑皮苷 A |
英文名 | mulberroside A |
别名 | 桑皮苷A 桑树苷A 桑皮苷 A 桑皮苷A对照品, 桑皮苷A(标准品) 桑皮苷A(分析标准品) 桑皮苷A, 来源于桑树 MULBERROSIDE A 桑皮苷A |
英文别名 | mulberroside A 2,5'-Dihydroxy-4,3'-bis(β-D-glucopyranosyloxy)-trans-stilbene 2,5'-Dihydroxy-4,3'-bis(beta-D-glucopyranosyloxy)-trans-stilbene b-D-Glucopyranoside,3-[(1E)-2-[4-(b-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl β-D-Glucopyranoside, 3-[(1E)-2-[4-(β-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl 3-{(E)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl}-5-hydroxyphenyl beta-D-glucopyranoside 2-(4-hydroxy-1,3-thiazol-3-ium-3-yl)ethyl [2-(octadecylcarbamoyloxymethyl)oxolan-2-yl]methyl phosphate beta-D-Glucopyranoside 3-[(1E)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl |
CAS | 102841-42-9 |
化学式 | C26H32O14 |
分子量 | 568.52 |
InChI | InChI=1/C26H32O14/c27-9-17-19(31)21(33)23(35)25(39-17)37-14-4-3-12(16(30)8-14)2-1-11-5-13(29)7-15(6-11)38-26-24(36)22(34)20(32)18(10-28)40-26/h1-8,17-36H,9-10H2/b2-1+/t17-,18-,19-,20-,21+,22+,23-,24-,25-,26-/m1/s1 |
密度 | 1.654 |
熔点 | 235-236o C |
沸点 | 954.7±65.0 °C(Predicted) |
比旋光度 | -78 (c, 0.88 in MeOH) |
闪点 | 531℃ |
蒸汽压 | 0mmHg at 25°C |
溶解度 | DMSO (微溶,超声处理),甲醇 (微溶) |
折射率 | 1.741 |
酸度系数 | 9.03±0.40(Predicted) |
存储条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
外观 | 固体 |
颜色 | White to Off-White |
物化性质 | 白色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于桑白皮。 |
MDL号 | MFCD16294844 |
体内研究 | Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic micem. Animal Model: Male Kun-Ming mice (20±2 g) Dosage: 5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight Administration: Orally initiated at 9:00 a.m. Result: 10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal. |
海关编号 | 29389090 |
参考资料 展开查看 | 1. 赵婷婷, 魏华, 陈两绵,等. 桑不同药用部位HPLC指纹图谱比较研究[J]. 中国药学杂志, 2017(07):45-51. 2. [IF=3.571] Ya-Nan Jia et al."Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs."J Agr Food Chem. 2019;67(19):5521–5529 |
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