中文名 | 淀粉-Β-蛋白片段12-28 |
英文名 | H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH |
别名 | 淀粉-Β-蛋白片段12-28 淀粉样肽 AMYLOID Β-PROTEIN (12-28) |
英文别名 | BETA-AMYLOID (12-28) AMYLOID BETA-PROTEIN (12-28) AMYLOID, BETA- (12-28), HUMAN BETA-AMYLOID PEPTIDE [12-28], HUMAN AMYLOID BETA-PROTEIN FRAGMENT 12-28 AMYLOID-BETA PROTEIN (12-28), HUMAN ALZHEIMER'S DISEASE BETA-PROTEIN (12-28) H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH |
CAS | 107015-83-8 |
化学式 | C89H135N25O25 |
分子量 | 1955.18 |
存储条件 | −20°C |
体外研究 | β-amyloid (12-28) may exert dysregulation cognitive effects by means of defective coordination of potassium channel function in nerve, glia and endothelial cells. β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure. 2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. 3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing. 4. Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments. Methods vary depends on the downstream applications. |
WGK Germany | 3 |
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