中文名 | R-α-硫辛酸 |
英文名 | R-alpha-Lipoic Acid |
别名 | 右旋硫辛酸 R(+)硫辛酸 R-α-硫辛酸 R(+)-硫辛酸 R-(+)-硫辛酸 -ALPHA-硫辛酸 (R)-6,8-硫辛酸 (R)-6,8-二硫辛酸 R-(+)- ALPHA-硫辛酸 (R)-(+)-1,2-二硫戊环基-3-戊酸 (R)-5-(1,2-二硫杂环戊烷-3-基)戊酸 (R)-(+)-α-硫辛酸 |
英文别名 | D-lipoic acid R-Alpha Lipoic Acid R-alpha-Lipoic Acid (R)-(+)-1,2-Dithiola R(+)Alpha Lipoic Acid R(+)alpha-lipoic acid R-(+)-alpha-Lipoic acid 5-[(3R)-dithiolan-3-yl]valeric acid 5-[(3R)-dithiolan-3-yl]pentanoic acid (R)-(+)-1,2-Dithiolane-3-pentanoic acid (R)-(+)-1,2-Dithiolane-3-Pentanoic Acid (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid 5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid (R)-Thioctic Acid(R)-1,2-Dithiolane-3-valeric Acid |
CAS | 1200-22-2 |
EINECS | 638-752-2 |
化学式 | C8H14O2S2 |
分子量 | 206.33 |
InChI | InChI=1/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1 |
密度 | 1.218±0.06 g/cm3(Predicted) |
熔点 | 48-52°C(lit.) |
沸点 | 185-195 °C(Press: 0.5 Torr) |
比旋光度 | D23 +104° (c = 0.88 in benzene) |
闪点 | >230°F |
溶解度 | 乙腈 (微溶),氯仿 (微溶),DMSO |
折射率 | 114 ° (C=1, EtOH) |
酸度系数 | 5.4(at 25℃) |
存储条件 | -20°C |
敏感性 | `sensitive` to light, heat, air and humidity |
外观 | 固体 |
颜色 | Light Yellow to Yellow Low-Melting |
Merck | 14,9326 |
MDL号 | MFCD01631142 |
体外研究 | Lipoic acid ((R)-(+)-α-Lipoic acid) is the form biosynthesized in humans which is essential for aerobic metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) is the nutritionally and therapeutically preferred form due to its "vitamin-like" role in metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) and S-(-)-α-Lipoic acid) constitute the racemic mixture Lipoic acid. Only the Lipoic acid ((R)-(+)-α-Lipoic acid) exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Lipoic acid ((R)-(+)-α-Lipoic acid) has been suggested to be nutritionally and therapeutically preferred form as antioxidant. |
风险术语 | R22 - 吞食有害。 R36/38 - 刺激眼睛和皮肤。 |
安全术语 | S20 - 使用时不得进食、饮水。 S36 - 穿戴适当的防护服。 S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S35 - 请小心处理该物质及其容器。 |
WGK Germany | 3 |
海关编号 | 29349990 |
下游产品 | (+/-)-二氢硫辛酸 |
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