1374601-40-7
BRD4770(BRD4770)
CAS: 1374601-40-7
化学式: C25H23N3O3
| 中文名 | BRD4770 |
| 英文名 | BRD4770 |
| 别名 | 化合物BRD4770 EHMT2抑制剂(BRD4770) |
| 英文别名 | BRD4770 CS-1814 BRD-4770 BRD 4770 Methyl 2-benzamido-1-(3-phenylpropyl)benzimidazole-5-carboxylate methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate Methyl-2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylate 2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate BRD4770 |
| CAS | 1374601-40-7 |
| EINECS | 802-776-3 |
| 化学式 | C25H23N3O3 |
| 分子量 | 413.47 |
| 密度 | 1.21±0.1 g/cm3(Predicted) |
| 溶解度 | DMSO: 可溶5mg/mL，澄清 (温热) |
| 酸度系数 | 12.12±0.43(Predicted) |
| 存储条件 | 2-8°C |
| 外观 | 粉末 |
| 颜色 | white to beige |
| 体外研究 | BRD4770 reduces cellular levels of di- and trimethylated H3K9 via inhibition of G9a, induces senescence, and inhibits both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. The combination of gossypol and BRD4770 increases LC3-II levels and the autophagosome number, and thus acts in synergy to induce cell death in PANC-1 cells. |
| 危险品标志 | Xn - 有害物品 |
| 风险术语 | 22 - 吞食有害。 |
| WGK Germany | 3 |
1374601-40-7 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.419 ml | 12.093 ml | 24.186 ml |
| 5 mM | 0.484 ml | 2.419 ml | 4.837 ml |
| 10 mM | 0.242 ml | 1.209 ml | 2.419 ml |
| 5 mM | 0.048 ml | 0.242 ml | 0.484 ml |
最后更新：2024-01-02 23:10:35
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