中文名 | 芦荟甙 |
英文名 | aloin |
别名 | 坝巴甙 芦荟苷 芦荟甙 芦荟素 巴白洛英 芦荟大黄素甙 芦荟甙提取物 10-吡喃葡萄糖基-1,8-二羟基-3-羟甲基-9(10H)-蒽酮 |
英文别名 | aloin Aloin Barbaloin barbaloin from aloe barbadensis*miller leaves 10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone 10-beta-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone 1,8-Dihydroxy-10-(beta-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone 1,5-anhydro-1-[4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl]hexitol 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl beta-D-glucopyranoside (1S)-1,5-anhydro-1-[(9R)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl]-D-glucitol (10R)-1,8-dihydroxy-3-(hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]-10H-anthracen-9-one (10R)-1,8-dihydroxy-3-methylol-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]-10H-anthracen-9-one (10R)-1,8-Dihydroxy-3-(hydroxymethyl)-10-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-10H-anthracen-9-one (10R)-1,8-dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-10H-anthracen-9-one 1,8-dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]-10H-anthracen-9-one 10-Glucopyranosyl-1,8-dihydro-3-(hydroxymethyl)-9-anthracenone, (10S)-beta-D-Glucopyranoside-aloe, Aloin A, Aloe-Emodin, Moquizone |
CAS | 1415-73-2 5133-19-7 |
EINECS | 610-650-2 |
化学式 | C21H22O9 |
分子量 | 418.39 |
InChI | InChI=1/C21H22O9/c22-6-8-4-10-14(21-20(29)19(28)17(26)13(7-23)30-21)9-2-1-3-11(24)15(9)18(27)16(10)12(25)5-8/h1-5,13-14,17,19-26,28-29H,6-7H2/t13-,14?,17-,19+,20-,21+/m1/s1 |
密度 | 1.648g/cm3 |
熔点 | 148-149°; monohydrate, mp 70-80° |
沸点 | 752.602°C at 760 mmHg |
比旋光度 | +21°(water) |
闪点 | 267.997°C |
蒸汽压 | 0mmHg at 25°C |
溶解度 | 易溶于吡啶,溶于冰醋酸,甲酸,丙酮,醋酸甲酯,以及乙醇等。 |
折射率 | 1.741 |
存储条件 | 2-8℃ |
外观 | 黄色或淡黄色结晶粉末 |
MDL号 | MFCD00151160 |
危险品标志 | Xi - 刺激性物品 |
风险术语 | R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36 - 穿戴适当的防护服。 |
参考资料 展开查看 | 1. 刘渭滨, 葛明建, 叶小叶,等. 芦荟苷联合顺铂对非小细胞肺癌细胞的影响研究[J]. 中国临床药理学杂志, 2020, v.36;No.304(02):56-59. 2. 吉惠杰, 杨艳俊, 薛俊礼,等. 超声波提取芦荟中芦荟苷的工艺研究[J]. 黑龙江农业科学, 2015(2):94-98. 3. 钱文慧, 刘文雅, 龚光明,等. 槲-芦美白防晒凝胶的制备及体外透皮行为考察[J]. 中国药师, 2020, v.23(06):97-101. 4. Jiang, Kangfeng, et al. "Barbaloin protects against lipopolysaccharide (LPS)-induced acute lung injury by inhibiting the ROS-mediated PI3K/AKT/NF-κB pathway." International immunopharmacology 64 (2018): 140-150.https://doi.org/10.1016/j.intimp.2018.08.023 5. [IF=3.361] Kangfeng Jiang et al."Barbaloin protects against lipopolysaccharide (LPS)-induced acute lung injury by inhibiting the ROS-mediated PI3K/AKT/NF-κB pathway."Int Immunopharmacol. 2018 Nov;64:140 6. [IF=4.36] Gaofeng Shi et al."Aloe vera mitigates dextran sulfate sodium-induced rat ulcerative colitis by potentiating colon mucus barrier."J Ethnopharmacol. 2021 Oct;279:114108 7. [IF=2.391] Zhang Xiao et al."Graphene oxide exhibited positive effects on the growth of Aloe vera L."Physiol Mol Biol Pla. 2021 Apr;27(4):815-824 8. [IF=4.451] Furong Wang et al.Network pharmacology combined with metabolomics to investigate the anti-hyperlipidemia mechanism of a novel combination.J Funct Foods. 2021 Dec;87:104848 9. [IF=2.552] Wang Sha et al."A newly isolated human intestinal strain deglycosylating flavonoid C-glycosides."ARCHIVES OF MICROBIOLOGY. 2022 Jun;204(6):1-8 |
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