149385-65-9_化工百科

中文名	异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸
英文名	H-ILE-ILE-GLY-LEU-MET-OH
别名	AMYLOID Β肽(31-35) 异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸淀粉样肽 AMYLOID Β-PROTEIN (31-35)
英文别名	IIGLM ILE-ILE-GLY-LEU-MET BETA-AMYLOID (31-35) β-Amyloid 31-35(TFA) H-ILE-ILE-GLY-LEU-MET-OH AMyloid b-Protein (31-35) AMYLOID BETA-PROTEIN (31-35) AMYLOID-BETA PROTEIN (31-35), HUMAN, MOUSE, RAT Isoleucinyl-isoleucinyl-glycinyl-leucinyl-methionine
CAS	149385-65-9
化学式	C25H47N5O6S
分子量	545.74
密度	1.137±0.06 g/cm3(Predicted)
沸点	866.4±65.0 °C(Predicted)
酸度系数	3.24±0.10(Predicted)
存储条件	−20°C
体外研究	β-Amyloid (31-35) is a functional cytotoxic domain of Aβ peptide. β-Amyloid (31-35) increases the phosphorylation of biotinylated Aβ(1-40), enhances CDK-1 activity, and also inhibits binding of Aβ to cyclin B1. β-Amyloid (31-35) is cytotoxic, and such an effect can be inhibited by olomoucine in differentiated human teratocarcinoma cell line, Ntera 2/cl-D1 (NT-2) neurons. β-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure. 2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 °C. 3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing. 4. Next, the solution was age 48h at 4-8 °C. The sample was then centrifuged at 14000g for 10 min at 4-8 °C; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments. Methods vary depends on the downstream applications.

北京索莱宝科技有限公司

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产品名: β-Amyloid (31-35) 去供应商网站查看询盘
CAS: 149385-65-9
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上海吉至生化科技有限公司

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上海麦克林生化科技股份有限公司

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产品名: β-Amyloid 31-35 去供应商网站查看询盘
CAS: 149385-65-9
产地: 上海
规格: A882181
价格: 5mg-1516,1mg-759
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上海源叶生物科技有限公司

产品名: 异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸去供应商网站查看询盘
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