中文名 | 高精氨酸 |
英文名 | H-Homoarg-OH |
别名 | 類鳥氨酸 高精氨酸 L-高精氨酸 H-高精氨酸 |
英文别名 | L-HoArg l-lysin H-HAR-OH NSC 27429 H-HoArg-OH H-HOARG-OH H-HOMOARG-OH Homoarginine H-Homoarg-OH L-Homoarginine L-HOMOARGININE l-n(sup6)-amidinolysine L-N(sup 6)-Amidinolysine Lysine, N(sup 6)-amidino-, L- n(sup6)-(aminoiminomethyl)-l-lysin L-Lysine, N(sup 6)-(aminoiminomethyl)- L-Lysine, N6-(aminoiminomethyl)- (9CI) L-ALPHA-AMINO-EPSILON-GUANIDINOHEXANOIC ACID |
CAS | 156-86-5 |
化学式 | C7H16N4O2 |
分子量 | 188.23 |
InChI | InChI=1/C7H16N4O2/c8-5(6(12)13)3-1-2-4-11-7(9)10/h5H,1-4,8H2,(H,12,13)(H4,9,10,11)/t5-/m1/s1 |
密度 | 1.39±0.1 g/cm3(Predicted) |
熔点 | 207-209 °C |
沸点 | 376.3±52.0 °C(Predicted) |
闪点 | 181.4°C |
蒸汽压 | 1.06E-06mmHg at 25°C |
折射率 | 1.586 |
酸度系数 | 2.52±0.24(Predicted) |
存储条件 | Keep in dark place,Inert atmosphere,2-8°C |
外观 | 白色结晶粉末 |
MDL号 | MFCD00237108 |
体外研究 | It is found that H-HoArg-OH (L-homoarginine), a homologue of arginine, is a strong inhibitor of human bone and liver alkaline phosphatase while it has virtually no effect on intestinal and placental alkaline phosphatases unlike H-HoArg-OH which inhibits intestinal and placental alkaline phosphatases but not the liver and bone enzymes. These four tissues mentioned are the major contributors to the serum alkaline phosphatase. It is also indicated that low levels of the endogenous amino acid H-HoArg-OH are linked to cardiovascular disease. |
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