1631164-24-3
BAY-784(BAY-784)
CAS: 1631164-24-3
化学式: C29H26ClF4N3O5S2
| 中文名 | BAY-784 |
| 英文名 | BAY-784 |
| 别名 | 化合物 T10475 |
| 英文别名 | BAY-784 BAY1214784 (S)-N-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-2-cyclopropyl-1-((4-fluorophenyl)sulfonyl)- |
| CAS | 1631164-24-3 |
| 化学式 | C29H26ClF4N3O5S2 |
| 分子量 | 672.11 |
| 体内研究 | BAY-784 (0.5, 3, 10, and 30 mg/kg; 24 hours; single p.o.) suppresses the plasma luteinizing hormone (LH) concentration in ovariectomized (OVX) rats in a dose-dependent manner. Animal Model: OVX rats Dosage: 0.5, 3, 10, and 30 mg/kg (Pharmacokinetic Analysis) Administration: Single p.o. Result: ED 50 =4.5 mg/kg (4/8 h). The t 1/2 =13-17 h, 18 h, and 7 h for male Wistar rat, female beagle, and female cynomolgus, respectively. |
