中文名 | 盐酸莫西沙星 |
英文名 | Moxifloxacin hydrochloride |
别名 | 盐酸莫西沙星 莫西沙星HCL 莫西沙星[盐酸] 莫西沙星及其中间体 盐酸莫西沙星(标准品) 莫西沙星盐酸盐溶液,100PPM 莫西沙星盐酸盐溶液, 1000PPM 1-环丙基-7-(S,S-2,8-重氮-二环[4.3.0]壬烷-8-基)-6-氟-8-甲氧-1,4-二氢-4-氧-3-喹啉羧酸盐酸盐 |
英文别名 | ACTIRA AVALOX PROFLOX BAY-12-8039 BAY12-8039 HCl MOXIFLOXACIN HCL Moxifloxacin HCl USP Moxifloxacin hydrochloride Moxifloxacin and intermediates Moxifloxacin HCl (Monohydrate) Moxifloxacin hydrochloride Solution, 1000ppm 1-CYCLOPROPYL-7-[(S,S)-2,8-DIAZA-BICYCLO[4.3.0]NON-8-YL]-6-FLUORO-8-METHOXY-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID HYDROCHLORIDE (1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO- 8-METHOXY-7- [(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE |
CAS | 186826-86-8 |
EINECS | 641-756-7 |
化学式 | C21H25ClFN3O4 |
分子量 | 437.8923032 |
InChI | InChI=1/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1H |
InChIKey | IDIIJJHBXUESQI-DFIJPDEKSA-N |
熔点 | Slightly yellow to yellow crystalline powder, mp 324-325° |
沸点 | 636℃ |
比旋光度 | 25D -256° (c = 0.5 in water) |
闪点 | >110°(230°F) |
水溶性 | Sparingly soluble in water. Soluble in DMSO |
蒸汽压 | 4.56E-17mmHg at 25°C |
溶解度 | H2O: 可溶物5mg/mL,澄清 (温热) |
存储条件 | 2-8°C |
外观 | 粉末 |
颜色 | white to beige |
BRN | 8377447 |
MDL号 | MFCD00949117 |
WGK Germany | 2 |
RTECS | VB1983750 |
Hazard Class | IRRITANT |
上游原料 | 硫酸 丙二酸二乙酯 醋酸 六水三氯化铁 氘代乙二醇 乙酐 氰化亚铜 |
参考资料 展开查看 | 1. 石庆新,杨阳,蔡莺莺,周铁丽.耐多药结核分枝杆菌对喹诺酮药物的耐药特性及分子机制的研究[J].浙江医学,2019,41(06):521-524+528. 2. [IF=18.808] Min Gong et al."Flexible Breathable Nanomesh Electronic Devices for On-Demand Therapy."Adv Funct Mater. 2019 Jun;29(26):1902127 3. [IF=7.514] Bolong Fang et al."Glucose oxidase-induced colorimetric immunoassay for qualitative detection of danofloxacin based on iron (Ⅱ) chelation reaction with phenanthroline."Food Chem. 2020 Oct;328:127099 4. [IF=6.057] Song Hu et al."Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food."Talanta. 2020 Nov;219:121245 5. [IF=2.363] Li Xie et al."A sensitive EZMTT method provides microscale, quantitative and high-throughput evaluation of drug efficacy in the treatment of Mycobacterium tuberculosis infectious diseases."J Microbiol Meth. 2021 Feb;181:106136 |
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