241479-67-4
艾沙康唑(Isavuconazole)
CAS: 241479-67-4
化学式: C22H17F2N5OS
| 中文名 | 艾沙康唑 |
| 英文名 | Isavuconazole |
| 别名 | 艾沙康唑 艾莎康唑 爱莎康唑 埃沙康唑 硫酸艾沙康唑 艾沙康唑中间体M9 |
| 英文别名 | BAL-4815 RO-0094815 Isavucozole Isaconazole Isavuconazole Isavuconazonium Isavuconazole(BAL-4815 4-(2-((2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)thiazol-4-yl)benzonitrile 4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile 4-[2-[(2R)-(2,5-Difluorophenyl)-2-hydroxy-(1R)-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]thiazol-4-yl]benzonitrile 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile |
| CAS | 241479-67-4 |
| EINECS | 1592732-453-0 |
| 化学式 | C22H17F2N5OS |
| 分子量 | 437.47 |
| 密度 | 1.38 |
| 熔点 | 89 - 91oC |
| 沸点 | 678.0±65.0 °C(Predicted) |
| 溶解度 | 氯仿 (微溶) 、甲醇 (微溶) |
| 酸度系数 | 11.42±0.29(Predicted) |
| 存储条件 | 2-8°C |
| 外观 | 固体 |
| 颜色 | Off-White to Beige |
| 体外研究 | Isavuconazole (BAL-4815) shows good activity against all Candida spp., with active MIC 50 of 0.004 mg/L. The MIC 50 s/MIC 90 s range from 0.002/0.004 mg/L for C. albicans to 0.25/0.5 mg/L for C. glabrata . Isavuconazole has potent in vitro activity against most common Aspergillus species, Purpureocillium lilacinum , and Scedosporium apiospermum . Isavuconazole shows potent activity against molds, yeasts, and dimorphic fungi. Rhizopus isolates have MIC values to isavuconazole as low as 0.12 µg/mL with others as high as 32 µg/mL. In the study of pharmacokinetics and pharmacodynamics of isavuconazole against the GFP transformant, F/11628, NIH 4215, and F/16216, the modal MICs of isavuconazole are 1, 8, 1, 4 mg/L, respectively. |
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产品名: 4-(2-((2R,3R)-3-(2,5-二氟苯基)-3-羟基-4-(1H-1,2,4-三唑-1-基)丁-2-基)噻唑-4-基)苯甲腈 去供应商网站查看 询盘CAS: 241479-67-4
产地: 中国上海
包装: 50mg
规格: 98%
价格: 3906.00
库存: 现货
电话: 400-900-4166
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产品描述: 中文名：4-(2-((2R,3R)-3-(2,5-二氟苯基)-3-羟基-4-(1H-1,2,4-三唑-1-基)丁-2-基)噻唑-4-基)苯甲腈 英文名:Isav 更多
现货供应
产品名: 4-(2-((2R,3R)-3-(2,5-二氟苯基)-3-羟基-4-(1H-1,2,4-三唑-1-基)丁-2-基)噻唑-4-基)苯甲腈 去供应商网站查看 询盘CAS: 241479-67-4
产地: 中国上海
包装: 50mg
规格: 98%
价格: 3906.00
库存: 现货
电话: 400-900-4166
手机: 18017137653
电子邮件: 3007523013@qq.com
QQ: 3007523013
微信: 18017137653
产品描述: 中文名：4-(2-((2R,3R)-3-(2,5-二氟苯基)-3-羟基-4-(1H-1,2,4-三唑-1-基)丁-2-基)噻唑-4-基)苯甲腈 英文名:Isav 更多
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