25913-34-2_化工百科

中文名	Tinoridine hydrochloride
英文名	ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride
别名	盐酸替诺立定盐酸替诺立定杂质 2-氨基-6-苄基-4,5,6,7-四氢噻吩并[2,3-C]吡啶-3-羧酸乙酯盐酸盐 2-氨基-6-苄基-4,5,6,7-四氢噻吩并[2,3-C]吡啶-3-甲酸乙酯盐酸盐
英文别名	Dimaten Nonflamin Einecs 247-342-9 Tinoridine hydrochloride Tinoridine Hydrochloride Tenocyclidine hydrochloride 2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-C)pyridine monohydrochloride ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride Thieno(2,3-C)pyridine-3-carboxylic acid, 2-amino-4,5,6,7-hexahydro-6-(phenylmethyl)-, ethyl ester, monohydrochloride
CAS	25913-34-2
EINECS	247-342-9
化学式	C17H21ClN2O2S
分子量	352.87884
熔点	234-235° (dec)
存储条件	Keep in dark place,Inert atmosphere,Room temperature
体外研究	Tinoridine reduces a stable free radical, diphenyl-p-picrylhydrazyl, in the molar ratio of about 1:2, indicating its free radical scavenging ability. Tinoridine inhibits the lipid peroxidation in rat liver microsomes induced by xanthine-xanthine oxidase system in the presence of ADP and Fe 2+ , in which hydroxyl radical is formed. Tinoridine is demonstrated to be oxidized in the course of the lipid peroxidation by following the fluorescence derived from the oxidation product of tinoridine. It is also oxidized by the xanthine-xanthine oxidase system in the presence of Fe 2+ , but its oxidation is slow in the absence of Fe 2+ and almost completely inhibited by catalase. Tinoridine is also oxidized by H 2 O 2 -Fe 2+ system producing OH (Fenton reaction), but it does not affect the reduction of cytochrome c caused by superoxide radical.
体内研究	CCl 4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted. Prior treatment of the animals with tinoridine (100 mg/kg) significantly reduces the CCl 4 -induced alterations in the enzyme activities, and a rapid recovery toward the normal values is observed.

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产品名: TinoridineHydrochloride;盐酸替诺立定去供应商网站查看询盘
CAS: 25913-34-2
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CAS: 25913-34-2
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产品描述: 中文名：2-氨基-6-苄基-4,5,6,7-四氢噻吩并[2,3-c]吡啶-3-羧酸乙酯盐酸盐英文名:Tinoridine HCl CAS:25913-34-2 更多

上海麦克林生化科技股份有限公司

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产品名: Tinoridine hydrochloride 去供应商网站查看询盘
CAS: 25913-34-2
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规格: T879969
价格: 5mg-308,25mg-884,1ml-291
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上海源叶生物科技有限公司

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产品名: Tinoridine hydrochloride 去供应商网站查看询盘
CAS: 25913-34-2
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