29307-60-6
京尼平-龙胆双糖苷(Genipin 1-Gentiobioside)
CAS: 29307-60-6
化学式: C23H34O15
| 中文名 | 京尼平-龙胆双糖苷 |
| 英文名 | Genipin 1-Gentiobioside |
| 别名 | 京尼平龙胆二糖苷 京尼平龙胆双糖苷 京尼平-龙胆双糖苷 京尼平-1-O-龙胆双糖苷 京尼平-2-Β-D-龙胆双糖苷 京尼平-1-Β-D-龙胆双糖苷 京尼平龙胆双糖苷(京尼平-1-Β-D-龙胆双糖苷) GENIPIN-1-B-D-GENTIOBIOSIDE 京尼平龙胆双糖苷 |
| 英文别名 | Genipin 1-Gentiobioside genipin 1-gentiobioside Genipin-1-O-gentiobioside genipin-1-β-D-gentiobioside Genipin-1-β-D-gentiobioside genipin-1-b-D-gentiobioside Genipin-1-b-D-gentiobioside Genipin 1-beta-gentiobioside Genipin 1-O-beta-D-gentiobioside methyl (1S,4aS,7aS)-1-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate Methyl (1S,4aS,7aS)-1-{[6-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy}-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate Cyclopenta[c]pyran-4-carboxylicacid, 1-[(6-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-1,4a,5,7a-tetrahydro-7-(hydroxyMethyl)-,Methyl ester, (1S,4aS,7aS)- cyclopenta[c]pyran-4-carboxylic acid, 1-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)-, methyl ester, (1S,4aS,7aS)- methyl (1S,4aS,7aS)-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate |
| CAS | 29307-60-6 |
| 化学式 | C23H34O15 |
| 分子量 | 550.51 |
| InChI | InChI=1/C23H34O15/c1-33-20(32)10-6-34-21(13-8(4-24)2-3-9(10)13)38-23-19(31)17(29)15(27)12(37-23)7-35-22-18(30)16(28)14(26)11(5-25)36-22/h2,6,9,11-19,21-31H,3-5,7H2,1H3/t9-,11-,12-,13-,14-,15-,16+,17+,18-,19-,21+,22-,23+/m1/s1 |
| 密度 | 1.63±0.1 g/cm3 (20 ºC 760 Torr) |
| 熔点 | 193-195°C |
| 沸点 | 835.3±65.0 °C(Predicted) |
| 闪点 | 281°C |
| 蒸汽压 | 2.16E-32mmHg at 25°C |
| 溶解度 | 可溶于甲醇、乙醇、DMSO等有机溶剂 |
| 折射率 | 1.647 |
| 酸度系数 | 12.78±0.70(Predicted) |
| 存储条件 | 2-8℃ |
| 敏感性 | Easily absorbing moisture |
| 外观 | 白色结晶粉末 |
| 物化性质 | 可溶于甲醇、乙醇、DMSO等有机溶剂，来源于为茜草科Rubiaceae植物栀子Gardenia jasminoides Ellis的干燥成熟果实。 |
| 体内研究 | Genipin 1-β-D-gentiobioside (Genipin gentiobioside) has moderate terminal elimination half-life (t 1/2 =1.65±0.87 h and 2.43±2.30 h for nomal rats (11.4 mg/kg) and cholestatic liver injury (CLI) rats (11.4 mg/kg), respectively). |
| 参考资料 展开查看 | 1. 刘宏 雷露静 白玉琴 等. 一测多评法同时测定蒙药三子散中7种指标成分[J]. 中国实验方剂学杂志 2017 023(018):58-63. 2. 苗琦 罗扬婧 方文娟 等. 利用一测多评法同时测定栀子中6种成分含量[J]. 江苏农业科学 2015 43(001):292-295. 3. 罗光明, 袁源见, 苗琦,等. 基于地形因子对栀子中6种成分含量的影响与生态适宜度研究[C]// 中国中药资源大会暨csnr中药及天然药物资源研究专业委员会学术年会. 2016. 4. 彭平, 张蓓, 杜菁,等. 基于天然麝香-牛黄和4个植物药味的安宫牛黄丸特征图谱质量表征研究[J]. 中草药, 2019(14). 5. 龚雨虹,罗光明,张风波,袁源见,李波,肖日传,谢晶,张博文.基于灰色关联度法评价栀子药材质量[J].中国实验方剂学杂志,2017,23(13):74-79. 6. 苗琦, 胡燕珍, 罗光明,等. 栀子全国生产区划中指标成分多波长 HPLC 方法建立[J]. 江苏农业科学, 2015, 43(002):300-302. 7. 苗琦, 罗光明, 罗扬婧, et al. 栀子多波长HPLC指纹图谱及化学模式识别研究[J]. 中草药, 2014, 45(21):3159-3164. 8. 袁源见, 罗光明, 魏春华,等. 栀子果皮颜色与6种成分的相关性研究[J]. 时珍国医国药, 2016, 027(006):1480-1483. 9. 邵坚, 罗光明, 朱继孝,等. 栀子炮制前后7种成分的比较研究[J]. 中草药, 2015, 46(11). 10. 田瑞华, 彭平, 刘希,等. 栀子药材的质量表征与产地的关联性研究[J]. 世界科学技术:中医药现代化, 2019(5):882-891. 11. 聂黎行,查祎凡,何风艳,刘静,李静,戴忠,于健东,马双成.牛黄清胃丸对照制剂的建立[J].药物分析杂志,2019,39(10):1738-1750. 12. 钱珺, 石燕红, 陈绍成,等. UPLC法测定栀子中的4种成分[J]. 中成药, 2016, 38(3):708-711. 13. 曹虹虹, 严维花, 郭爽,等. 基于多成分测定及指纹图谱评价不同产地栀子质量[J]. 中国中药杂志, 2019, v.44(18):196-203. 14. 曹虹虹, 严维花, 郭爽,等. 栀子姜炙工艺及姜炙前后化学成分变化研究[J]. 中国中药杂志, 2019(24). 15. 缪芝硕,钟益玲,李海丽,吴倩,邝鼎,唐伟卓.栀子枝7种成分LC-MS分析及HPLC-DAD测定[J].中成药,2021,43(01):117-123. 16. Wang, Lu, et al. "Characterization of interaction property of multi‐components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry." Rapid Communications in Mass Spectrometry 30 (2 17. Wang, Lu, et al. "Characterization of interaction property of multi‐components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry." Rapid Communications in Mass Spectrometry 30 (2 18. [IF=4.759] Lu Wang et al."A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectr 19. [IF=2.419] Lu Wang et al."Characterization of interaction property of multi-components in Gardenia jasminoides with aldose reductase by microdialysis combined with liquid chromatography coupled to mass spectrometry."Rapid Communications In Mass Spectrometry. 2016 Au 20. [IF=1.902] Zhi Rao et al."Multicomponent determination of traditional Chinese medicine preparation yin-zhi-huang injection by LC–MS/MS for screening of its potential bioactive candidates using HepaRG cells."Biomed Chromatogr. 2018 Feb;32(2):e4057 21. [IF=5.81] Bai Yongtao et al."Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Zhi-Zi-Hou-Po Decoction in Depression."Front Pharmacol. 2021 Oct;0:2575 22. [IF=5.81] Dong Rong et al."An Integrated Strategy for Rapid Discovery and Identification of Quality Markers in Gardenia Fructus Using an Omics Discrimination-Grey Correlation-Biological Verification Method."Front Pharmacol. 2021 Jun;0:1596 23. [IF=4.411] Chunnan Li et al."Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells."Molecules. 2019 Jan;24(21):3920 24. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC–MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243 25. [IF=2.447] Jianrong Chen et al."Anti‑inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos."Exp Ther Med. 2021 Jul;22(1):1-9 |
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产品名: 京尼平龙胆双糖苷 标准品 去供应商网站查看 询盘CAS: 29307-60-6
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现货供应
产品名: 京尼平龙胆双糖苷 标准品 去供应商网站查看 询盘CAS: 29307-60-6
产地: 北京
包装: 瓶
规格: SG8880-20mg,20mg,IG0960-5mg,5mg,IG0960-10mg,10mg,IG0960-20mg,20mg
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
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