中文名 | 3-(甲硫基)丙酸 |
英文名 | 3-(Methylthio)propionic acid |
别名 | 3-甲硫基丙酸 3-甲基硫代丙酸 3-(甲硫基)丙酸 3-(甲基硫代)丙酸 3-甲基硫代丙酸 3-(甲基硫代)丙酸 |
英文别名 | 4-Thiapentanoic acid 3-METHYLTHIO PROPIONATE 3-Methythiopropionic acid 3-METHYTHIOPROPIONIC ACID 3-METHYLTHIOPROPIONIC ACID 3-Methylthiopropionic Acid 3-(Methylthio)propionic acid 3-(methylsulfanyl)propanoate 3-METHYLMERCAPTOPROPIONIC ACID Propanoic acid, 3-(methylthio)- Propionic acid, 3-(methylthio)- 3-(Methylsulfanyl)propanoic acid |
CAS | 646-01-5 |
EINECS | 211-460-9 |
化学式 | C4H8O2S |
分子量 | 120.17 |
InChI | InChI=1/C4H8O2S/c1-7-3-2-4(5)6/h2-3H2,1H3,(H,5,6)/p-1 |
密度 | 1.160 |
熔点 | 16°C |
沸点 | 130°C 2mm |
闪点 | 130°C/15mm |
蒸汽压 | 0.00741mmHg at 25°C |
折射率 | 1.4884 |
酸度系数 | 4.29±0.10(Predicted) |
存储条件 | -20℃ |
外观 | 粉至块至清液 |
颜色 | White or Colorless to Light yellow |
BRN | 1743054 |
MDL号 | MFCD00059635 |
体外研究 | Methionine has consistently been shown to be the most toxic amino acid in experiments devised to assess the relative toxicity of dietary amino acids. 3-methylthiopropionate is an intermediate in methionine catabolism in rat and monkey liver in vitro . This pathway appears to account for a major portion of methionine oxidation in vitro . Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts directly related to the concentration of methionine in the medium. The first intermediate in the pathway may be the keto acid, which is then oxidatively decarboxylated to 3-methylthiopropionic acid. The purified 3-MTPA has antifungal activity in assays using F. oxysporum as a model fungus. Daily measurements of shoot and root length shows severe inhibition of seed germination and root and shoot development at concentrations above 12mg for partially purified extracts. 3-methylthiopropionic acid ethyl ester possesses potential anticarcinogenic properties by inducing differentiation in well-differentiated colon cancer cells. Treatment of RCM-1 cells for 4 days with 3-methylthiopropionic acid ethyl ester between the doses of 0.25 and 2 mM progressively increases the percent area occupied by duct structures relative to the control, and also induces an increase in the number and the maximum diameter of the ducts in each culture plate. |
风险术语 | 34 - 引起灼伤。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 |
危险品运输编号 | 3265 |
海关编号 | 29309090 |
Hazard Class | 8 |
Packing Group | II |
上游原料 | 甲醇 氢氧化钾 氯化钠 |
下游产品 | 3-甲硫基丙酸乙酯 |
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