3681-99-0
葛根素(puerarin)
CAS: 3681-99-0
化学式: C21H20O9
| 中文名 | 葛根素 |
| 英文名 | puerarin |
| 别名 | 葛根素 葛根黄酮 葛根素(分析标准品) 黄豆甙元-8-葡萄糖甙 4',7-二羟基-8-葡萄糖甙 8-Β-D-葡萄吡喃糖-4',7-二羟基异黄酮 8-beta-D-葡萄吡喃糖-4',7-二羟基异黄酮 |
| 英文别名 | puerarin Puerarine purerarin PSYCHOSINE Kudzu Extract PUERARIAROOT.P.E PUERARIN EXTRACT 8-GLUCOSYLDAIDZEIN Kudzu Root extract 8-glucosyldaidzein Pueraria root flavone DAIDZEIN-8-C-GLUCOSIDE Daidzein-8-C-glucoside 7-hydroxy-3-(4-hydroxyphenyl)- 7,4'-Dihydroxy-8-C-glucosylisoflavone 4',7-Dihydroxy-8-C-Glucosylisoflavone 7,4'-Dihydroxy-8-C-Glucosylisoflavone 1-n-Dodecylazacycloneptan-2-one Nizatidine 4H-1-Benzopyran-4-one,8-β-D-glucopyranosyl- 1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]hexitol 7-HYDROXY-3-[4-HYDROXYPHENYL]-1-BENZOPYRAN-4-ONE 8-[BETA-D-GLUCOPYRANOSIDE 7-hydroxy-3-[4-hydroxyphenyl]-1-benzopyran-4-one 8-[beta-D-glucopyranoside 8-beta-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 8-(Beta-D-Glucopyranosyl-7-Hydroxy-3-(4-Hydroxyphenyl)-4h-1-Benzopyran-4-One 4H-1-Benzopyran-4-one, 8-beta-D-glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)- (1S)-1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol (1xi)-1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-D-glucitol 7-Hydroxy-3-(4-Hydroxyphenyl)-8-[(2s,3s,4r,5r,6r)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Chromen-4-One |
| CAS | 3681-99-0 |
| EINECS | 609-296-1 |
| 化学式 | C21H20O9 |
| 分子量 | 416.38 |
| InChI | InChI=1/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21?/m1/s1 |
| InChIKey | HKEAFJYKMMKDOR-NCHCSYJDSA-N |
| 密度 | 1.614±0.06 g/cm3(Predicted) |
| 熔点 | 187-189°C |
| 沸点 | 688.0±55.0 °C(Predicted) |
| 闪点 | 245.1°C |
| 水溶性 | Soluble in DMSO or DMF. Slightly soluble in water or ethanol |
| 蒸汽压 | 7.06E-20mmHg at 25°C |
| 溶解度 | DMSO (微溶) 、甲醇 (微溶) |
| 折射率 | 1.719 |
| 酸度系数 | 6.46±0.20(Predicted) |
| 存储条件 | 2-8°C |
| 外观 | 粉末 |
| 颜色 | White to Off-white |
| 最大波长(λmax) | ['303nm(MeOH)(lit.)'] |
| BRN | 64198 |
| 物化性质 | 白色针状结晶，加热可溶于水、甲醇、乙醇，不溶于乙酸乙酯、氯仿、苯，来源于葛根块根。 |
| MDL号 | MFCD00076007 |
| 危险品标志 | F - 易燃物品 C - 腐蚀性物品  |
| 风险术语 | R11 - 高度易燃。 R34 - 引起灼伤。 |
| 安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 S45 - 若发生事故或感不适，立即就医(可能的话，出示其标签)。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 S16 - 远离火源。 |
| WGK Germany | 3 |
| RTECS | UO5216000 |
| FLUKA BRAND F CODES | 10 |
| 海关编号 | 29389090 |
| 上游原料 | 69655-50-1 |
| 参考资料 展开查看 | 1. 崔灵 张丽姝 陈萌萌 等. 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Shasha Jing, Huijun Zheng, Li Zhao, Lingbo Qu, Lanlan Yu,A novel electrochemical sensor based on WO3 nanorods-decorated poly(sodium 4-styrenesulfonate) functionalized graphene nanocomposite modified electrode for detecting of puerarin,Talanta,Volume 174 45. Renshu, Huang, et al. "Extraction technology of isoflavone from Dabie Mountain's Pueraria lobata and determination of its reducing power." Pakistan journal of pharmaceutical sciences 27 (2014). 46. Li, Na, et al. "Comparative Tissue Distribution of 6 Major Polyphenolic Compounds in Normal and Myocardial Ischemia Model Rats After Oral Administration of the Polygonum orientale L. Extract." Natural Product Communications 15.6 (2020): 1934578X20929447.ht 47. Huang, W, Wen, Z, Wang, M, Xu, B, Zhou, B, Li, X. Anticomplement and antitussive activities of major compound extracted from Chimonanthus nitens Oliv. leaf. Biomedical Chromatography. 2020; 34:e4736. https://doi.org/10.1002/bmc.4736 48. Zhang, Jifen, et al. 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[IF=5.396] Song Liu et al."The in silico and in vivo evaluation of puerarin against Alzheimer's disease."Food Funct. 2019 Feb;10(2):799-813 53. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56 54. [IF=3.645] Wenjie Wu et al."Simple, rapid, and environmentally friendly method for the separation of isoflavones using ultra-high performance supercritical fluid chromatography."J Sep Sci. 2017 Jul;40(13):2827-2837 55. [IF=3.361] Hongguang Zhang et al."Extraction of isoflavones from Puerariae lobata using subcritical water."Rsc Adv. 2018 Jun;8(40):22652-22658 56. [IF=2.896] Bo Li et al."Preparative separation of isoflavones in plant extract of Pueraria lobata by high performance counter-current chromatography."Anal Methods-Uk. 2015 Feb;7(4):1321-1327 57. [IF=2.19] Y.J. 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[IF=5.682] Hengyue Zhu et al."The isoflavone puerarin exerts anti-tumor activity in pancreatic ductal adenocarcinoma by suppressing mTOR-mediated glucose metabolism."Aging-Us. 2021 Dec 15; 13(23): 25089–25105 79. [IF=4.412] Haifan Liu et al."Pharmacokinetics, Prostate Distribution and Metabolic Characteristics of Four Representative Flavones after Oral Administration of the Aerial Part of Glycyrrhiza uralensis in Rats."MOLECULES. 2022 Jan;27(10):3245 80. [IF=5.34] Lei Jin et al."Simultaneous optimization of the extraction process of Yangyin Yiqi Huoxue prescription with natural deep eutectic solvents for optimal extraction yield and antioxidant activity: A comparative study of two models."PHYTOMEDICINE. 2022 Jul;102 81. [IF=2.552] Wang Sha et al."A newly isolated human intestinal strain deglycosylating flavonoid C-glycosides."ARCHIVES OF MICROBIOLOGY. 2022 Jun;204(6):1-8 82. [IF=11.614] Pengfei He et al."Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C-glycoside cleaving enzyme and an O- to C-glycoside isomerase."Acta Pharmaceutica Sinica B. 2022 May;: |
3681-99-0 - 简介
葛根素是一种提取自葛根的植物化合物。它具有多种生物活性和药理作用。
葛根素具有抗氧化、抗菌、抗炎和抗肿瘤等活性。它可以增强免疫力，减缓衰老，改善心血管健康，降低胆固醇，缓解更年期症状等。葛根素也被广泛用作一种天然保健品和草药。
葛根素主要通过提取葛根中的有效成分得到。一种常用的提取方法是使用乙醇、水或其他溶剂进行浸提和浓缩。然后，通过过滤和结晶，得到纯化的葛根素。
葛根素在正常使用剂量范围内一般是安全的，但过量使用可能会引发不适反应，如头晕、恶心、胃部不适等。对于孕妇、哺乳期妇女和儿童，以及对葛根素过敏的人群，应慎重使用或避免使用。
葛根素具有抗氧化、抗菌、抗炎和抗肿瘤等活性。它可以增强免疫力，减缓衰老，改善心血管健康，降低胆固醇，缓解更年期症状等。葛根素也被广泛用作一种天然保健品和草药。
葛根素主要通过提取葛根中的有效成分得到。一种常用的提取方法是使用乙醇、水或其他溶剂进行浸提和浓缩。然后，通过过滤和结晶，得到纯化的葛根素。
葛根素在正常使用剂量范围内一般是安全的，但过量使用可能会引发不适反应，如头晕、恶心、胃部不适等。对于孕妇、哺乳期妇女和儿童，以及对葛根素过敏的人群，应慎重使用或避免使用。
最后更新：2024-04-09 02:00:08
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产品名: 葛根素(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IP08401
产地: 北京
包装: 1ml/瓶
规格: IP08401-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
提供多种规格现货供应
产品名: 葛根素(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IP08401
产地: 北京
包装: 1ml/瓶
规格: IP08401-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
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