495-83-0
Tigloidin(Tigloidin)
CAS: 495-83-0
化学式: C13H21NO2
| 中文名 | Tigloidin |
| 英文名 | Tigloidin |
| 别名 | 惕各酰托品因 化合物 T13158 |
| 英文别名 | Tigloidin Tiglyssin tigloidine Tigloyltropine Tigloyltropeine 3α-Tigloyloxytropane Tigloyl pseudotropine 2-Methylcrotonic acid (1R,5S)-tropan-3β-yl ester |
| CAS | 495-83-0 |
| EINECS | 2078105 |
| 化学式 | C13H21NO2 |
| 分子量 | 223.314 |
| 密度 | 1.06±0.1 g/cm3(Predicted) |
| 沸点 | 290.2±33.0 °C(Predicted) |
| 溶解度 | DMSO |
| 酸度系数 | 10.03±0.40(Predicted) |
| 存储条件 | -20℃ |
| 体内研究 | Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats. |
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