5-甲氧基黄酮
5-甲氧基黄酮(5-Methoxyflavone)
CAS: 42079-78-7
化学式: C16H12O3
| 中文名 | 5-甲氧基黄酮 |
| 英文名 | 5-Methoxyflavone |
| 别名 | 甲氧基黄酮 5-甲氧基黄酮 |
| 英文别名 | 5-METHOXYFLAVONE 5-Methoxyflavone METHOXYFLAVONE, 5- 5-methoxy-2-phenyl-chromone 5-methoxy-2-phenylchromen-4-one 5-methoxy-2-phenyl-4-benzopyrone 5-methoxy-2-phenyl-chromen-4-one 5-Methoxy-2-phenyl-4H-1-benzopyran-4-one |
| CAS | 42079-78-7 |
| EINECS | 255-652-0 |
| 化学式 | C16H12O3 |
| 分子量 | 252.26 |
| 密度 | 1,155g/cm |
| 熔点 | 131-133°C |
| 沸点 | 422.5±45.0 °C(Predicted) |
| 折射率 | 1,548 |
| 存储条件 | 2-8℃ |
| 敏感性 | It will not decompose under normal conditions, and there is no dangerous reaction |
| 外观 | 粉末 |
| MDL号 | MFCD00016942 |
| 体外研究 | 5-Methoxyflavone (compound 1) is identified as a candidate compound endowed with the ability to inhibit DNA pol-β in multiple and to prevent cell-cycle initiation and subsequent neuronal apoptosis in Aβ-challenged primary neuronal cultures. 5-methoxyflavone (10-30 μM) is able to significantly enhance toxicity of MMS on 92TAg cells. 5-Methoxyflavone (1 or 10 μM) significantly reduces polymerase activity on a gapped substrate. 5-Methoxyflavone (5-MF, 0-100 μg/mL) results in a time dependent reduction in the levels of antiapoptotic proteins cFLIP, Mcl-1 and an increase in the proapoptotic protein BAX. 5-MF induces both TRAIL-R1(DR4) and TRAIL-R2 (DR5) in a time-dependent manner. |
| 体内研究 | 5-Methoxyflavone (100, 150 mg/kg, i.p) significantly decreases the latency time to loss of righting reflex. 5-Methoxyflavone (50, 100 and 150 mg/kg, i.p) exhibits a significant and dose-dependent reduction in the spontaneous locomotor activity. 5-Methoxyflavone (50, 100 mg/kg, i.p) reduces the rearing response. 5-Methoxyflavone (100, 125 and 150 mg/kg, i.p) completely abolishesed the grooming response similar to diazepam treated animals. |
| 危险品标志 | Xi - 刺激性物品 |
| 风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
| 安全术语 | S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S36 - 穿戴适当的防护服。 |
| WGK Germany | 3 |
| 下游产品 | 5-羟基黄酮 |
供应商列表
现货供应
产品名: 5-Methoxyflavone;5-甲氧基黄酮 去供应商网站查看 询盘CAS: 42079-78-7
产地: 北京
包装: 盒
规格: IM2280-25mg,25mg,IM2280-50mg,50mg
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
现货供应
产品名: 5-Methoxyflavone;5-甲氧基黄酮 去供应商网站查看 询盘CAS: 42079-78-7
产地: 北京
包装: 盒
规格: IM2280-25mg,25mg,IM2280-50mg,50mg
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销，欢迎来询
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