中文名 | 盐酸妥洛特罗 |
英文名 | tulobuterol hydrochloride |
别名 | 盐酸妥布特 盐酸妥洛特罗 盐酸妥布托罗 妥洛特罗盐酸 盐酸妥布特罗 妥布特罗盐酸盐 妥布特罗甲醇溶液标准物质 甲醇中妥布特罗溶液标准物质 妥布特罗盐酸盐溶液,100PPM 2-叔丁氨基-1-(2-氯苯基)乙醇 盐酸盐 (+|-)-2-氯-2-[(叔丁基氨基)甲基]苯甲醇盐酸盐 |
英文别名 | Atenos Ventaire TULOBUTEROL HG Tulobuterol Hcl Tulobuterol solution tulobuterol hydrochloride Tulobuterol hydrochloride API Tulobuterol Hydrochloride Solution, 100ppm α-[(tert.-Butylamino)methyl]-2-chlorobenzyl Alcohol Hydrochloride Benzenemethanol, 2-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-, hydrochloride (9CI) |
CAS | 56776-01-3 |
EINECS | 634-677-4 |
化学式 | C12H19Cl2NO |
分子量 | 264.19 |
InChI | InChI=1/C12H18ClNO.ClH/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13;/h4-7,11,14-15H,8H2,1-3H3;1H/t11-;/m0./s1 |
InChIKey | RSLNRVYIRDVHLY-UHFFFAOYSA-N |
熔点 | 159-163℃ |
水溶性 | Soluble in methanol or water. |
溶解度 | DMSO (微溶) 、甲醇 (微溶) |
存储条件 | 2-8°C |
敏感性 | Hygroscopic |
外观 | 整洁 |
颜色 | White |
Merck | 14,9811 |
MDL号 | MFCD00214398 |
体内研究 | In vivo effect of Tulobuterol is examined the on the contractility of diaphragm muscles prepared from mice (BALBs/c mice; 21.7 ± 0.2 g) treated with Endotoxin. Contractile parameters of force-frequency curves and twitch kinetics using untreated or treated diaphragm muscles at 0 (E0) and 4 (E4) hours after E. coli endotoxin (20 mg/kg) administration are measured. E0 and E4 diaphragm muscles are analyzed at 0, 12, and 24 h after transdermal Tulobuterol treatment. The force-frequency curves of E0 and E4 diaphragm muscles at three time points are not significantly changed each other, indicating that Tulobuterol patch restores the muscle contractility. Thus, diaphragm muscle contractility is maintained during 4 h of endotoxin administration with Tulobuterol patch for over 24 h. |
危险品标志 | Xn - 有害物品 |
风险术语 | 22 - 吞食有害。 |
WGK Germany | 3 |
RTECS | DN8785000 |
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