56776-32-0_化工百科

中文名	盐酸艾替伏辛
英文名	Etifoxine Hydrochloride
别名	盐酸艾替伏辛盐酸依替福辛艾替伏辛盐酸盐
英文别名	StresaM Etifoxine Hydrochloride HOE-36801 hydrochloride Etifoxine·hydrochloride 2-EthylaMino-6-chloro-4-Methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride 6-Chloro-N-ethyl-4-Methyl-4-phenyl-4H-3,1-benzoxazin-2-aMine Hydrochloride 6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride 6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminehydrochloride 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride
CAS	56776-32-0
EINECS	260-380-0
化学式	C17H18Cl2N2O
分子量	337.24362
熔点	ND
溶解度	DMSO: ≥ 5 mg/mL
存储条件	-20°C
外观	粉末
颜色	white to beige
体外研究	Etifoxine (EFX), at concentrations ranging from 10 to 300 μM (higher concentrations limited its solubility), produces a dose-dependent increase in the [3H]muscimol binding at equilibrium, to 155±2% of its control value at 300 μM EFX.
体内研究	Etifoxine competitively inhibits [ 35 S]TBPS binding with micromolar potency in rat brain. Etifoxine (3.125-50 mg/kg) exhibits more pronounced anxiolytic and anticonvulsant effects in the BALB/cByJ mice compared to the C57BL/6J mice. Animal Model: Six-week old BALB/cByJ and C57BL/6J mice (20-25 g). Dosage: 3.125-50 mg/kg. Administration: Intraperitoneal inhection. Result: Significantly increased the amount of time spent on the open arms at the 12.5 mg/kg dose when compared to vehicle (p = 0.009) in BALB/cByJ mice but produced no effect in C57B/6J mice. BALB/cByJ mice compared with C57BL/6J mice exhibited significantly (p < 0.012) lower plasma levels of the compound at 15 and 30 min.
危险品标志	Xn - 有害物品
风险术语	22 - 吞食有害。
WGK Germany	3

56776-32-0 - 配置溶液浓度参考

	1mg	5mg	10mg
1 mM	2.965 ml	14.826 ml	29.652 ml
5 mM	0.593 ml	2.965 ml	5.93 ml
10 mM	0.297 ml	1.483 ml	2.965 ml
5 mM	0.059 ml	0.297 ml	0.593 ml

最后更新：2024-01-02 23:10:35

上海吉至生化科技有限公司

现货供应

产品名: 艾替伏辛盐酸盐去供应商网站查看询盘
CAS: 56776-32-0
产地: 中国上海
包装: 10mg
规格: 99%
价格: 1098.00
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产品描述: 中文名：艾替伏辛盐酸盐英文名:Etifoxine hydrochloride CAS:56776-32-0 规格:99% 产地:中国上海

上海麦克林生化科技股份有限公司

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产品名: Etifoxine hydrochloride 去供应商网站查看询盘
CAS: 56776-32-0
产地: 上海
规格: E878412
价格: 10mg-953,5mg-676
库存: 7天内发货
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上海源叶生物科技有限公司

产品名: Etifoxine Hydrochloride 去供应商网站查看询盘
CAS: 56776-32-0
产地: 上海
规格: 99%
价格: 5mg 780,10mg 1100,50mg 3900,100mg 6800
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