58749-22-7
甘草查尔酮A((2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one)
CAS: 58749-22-7
化学式: C21H22O4
| 中文名 | 甘草查尔酮A |
| 英文名 | (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
| 别名 | 草查尔酮A 甘草查而酮 甘草查耳酮甲 甘草查耳酮A 甘草查尔酮A 甘草查而酮 A LICOCHALCONE A 甘草查尔酮A LICOCHALCONE A 甘草查尔酮A 标准品 |
| 英文别名 | Licochalcone-A LICOCHALCONE-A 7-Dimethoxycoumarin 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one (E)-3-[5-(1,1-DIMETHYL-2-PROPENYL)-4-HYDROXY-2-METHOXYPHENYL]-1-(4-HYDROXYPHENYL)-2-PROPEN-1-ONE (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)- 2-propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)- Soluble LICOCHALCONE A, Liposomal LICOCHALCONE A, LICOCHALCONE A NanoEmulsion, NanoActive LICOCHALCONE A |
| CAS | 58749-22-7 |
| EINECS | 635-678-2 |
| 化学式 | C21H22O4 |
| 分子量 | 338.4 |
| InChI | InChI=1/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+ |
| InChIKey | KAZSKMJFUPEHHW-DHZHZOJOSA-N |
| 密度 | 1.171±0.06 g/cm3(Predicted) |
| 熔点 | 100° |
| 沸点 | 532.6±50.0 °C(Predicted) |
| 闪点 | 186.9°C |
| 蒸汽压 | 5.88E-12mmHg at 25°C |
| 溶解度 | 溶于DMSO，甲醇 |
| 折射率 | 1.61 |
| 酸度系数 | 7.82±0.15(Predicted) |
| 存储条件 | -20°C |
| 外观 | 黄色固体 |
| BRN | 4534154 |
| 物化性质 | 黄色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于甘草根茎。 |
| MDL号 | MFCD01417903 |
| 危险品标志 | Xn - 有害物品 |
| 风险术语 | 20/21/22 - 吸入、皮肤接触及吞食有害。 |
| 安全术语 | 36/37 - 穿戴适当的防护服和手套。 |
| WGK Germany | 3 |
| RTECS | UB8755000 |
| 参考资料 展开查看 | 1. 王梨明, 范志浩, 范晓丽,等. 甘草查尔酮A对人骨肉瘤细胞增殖、凋亡的影响及其机制[J]. 广西医学, 2019, 41(012):1528-1531. 2. 郭婉怡,袁蓓,汪倩,苏晓慧.甘草查尔酮A通过调控MAPK信号通路抑制MH7A细胞增殖并诱导凋亡[J].中国实验方剂学杂志,2020,26(24):68-74. 3. Yang, Zhenzhong, et al. "Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe." Journal of Pharmaceutical Analysis (2020).https://doi.org/10.1016/ 4. Tian D-D, Wang W, Wang H-N, Sze SCW, Zhang Z-J. Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats. Molecules. 2016; 21(6):696. https://doi.org/10.3390/molecules 5. [IF=2.896] Tian-Ming Wang et al."Simultaneous determination of 14 major components in Longhu Rendan pills by ultra-high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry."Anal Methods-Uk. 2014 Apr;6(9):2923-2929 6. [IF=4.769] Zhenzhong Yang et al."Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe."J Pharm Anal. 2020 Nov;: 7. [IF=4.451] Zijian Wang et al."Licorice flavonoids nanoparticles prepared by liquid antisolvent re-crystallization exhibit higher oral bioavailability and antioxidant activity in rat."J Funct Foods. 2019 Jun;57:190 8. [IF=2.629] Li Tingting et al."Quality Assessment of Licorice Based on Quantitative Analysis of Multicomponents by Single Marker Combined with HPLC Fingerprint."Evid-Based Compl Alt. 2021;2021:8834826 9. [IF=5.545] Yuxuan Han et al."Multi-dimensional "projection" - the impact of abiotic stresses on the content of seven active compounds and expression of related genes in Glycyrrhiza uralensis Fisch."Environ Exp Bot. 2022 May;197:104846 10. [IF=6.244] Yalei Wang et al."Exploration of the Potential Mechanism of Qi Yin San Liang San Decoction in the Treatment of EGFRI-Related Adverse Skin Reactions Using Network Pharmacology and In Vitro Experiments.."Front Oncol. 2022 Mar;12:790713-790713 11. [IF=1.978] Chen Ming-jun et al."Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3."Chin J Integr Med. 2022 Apr;:1-10 |
58749-22-7 - 简介
甘草查尔酮A是一种天然产物，也被称为甘草酮酸A。它是从甘草根部提取的一种化合物。
甘草查尔酮A的物理性质是无色结晶体，具有苦味。
它具有抗氧化、抗炎、抗菌和抗肿瘤的功效。
甘草查尔酮A的制法一般采用从甘草根部提取的方法。提取后，通过结晶、溶剂萃取和柱层析等分离纯化方法得到甘草查尔酮A。
甘草查尔酮A的物理性质是无色结晶体，具有苦味。
它具有抗氧化、抗炎、抗菌和抗肿瘤的功效。
甘草查尔酮A的制法一般采用从甘草根部提取的方法。提取后，通过结晶、溶剂萃取和柱层析等分离纯化方法得到甘草查尔酮A。
最后更新：2024-04-09 21:31:57
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产品名: 甘草查尔酮A(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IL01101
产地: 北京
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规格: IL01101-1ml
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提供多种规格现货供应
产品名: 甘草查尔酮A(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IL01101
产地: 北京
包装: 1ml/瓶
规格: IL01101-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
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