84746-43-0
Small Cardioactive Peptide B SCPB(Small Cardioactive Peptide B SCPB)
CAS: 84746-43-0
化学式: C52H80N14O11S2
| 中文名 | Small Cardioactive Peptide B SCPB |
| 英文名 | Small Cardioactive Peptide B SCPB |
| 英文别名 | SCPB MNYLAFPRM-NH2 SMALL CARDIOACTIVE PEPTIDE B CARDIOACTIVE PEPTIDE B (SMALL) Small Cardioactive Peptide B SCPB SCPB Cardioactive Peptide B (sMall) MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2 MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET AMIDE H-MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2 |
| CAS | 84746-43-0 |
| 化学式 | C52H80N14O11S2 |
| 分子量 | 1141.41 |
| 存储条件 | −20°C |
| 体外研究 | Small cardioactive peptide B (SCP B ) is a neurally active peptide endogenous to Aplysia . Small cardioactive peptide B (SCP B ) possesses cardioexcitatory effects in Aplysia and reported a threshold concentration of 0.01 nM for both native and synthetic Small cardioactive peptide B (SCP B ) stimulated effects on the isolated heart. Effects of Small Cardioactive Peptide B (SCP B ) on the physiology of the isolated heart and gill preparations from the mollusc Aplysia californica were examined. In addition, the effects of Small Cardioactive Peptide B (SCP B ) and FMRFamide (Phe-Met-Arg-Phe-NH2) on adenylate cyclase activity are compared in particulate fractions of heart and gill tissues, respectively. Small Cardioactive Peptide B (SCP B ) is found to exert dose-dependent, reversible changes in cardiac activity when perfused through the isolated heart. The EC 50 values effecting changes in heart rate and force of contraction are 0.03 and 0.3 nM, respectively; minimum concentrations find to effect changes in heart rate and force of contraction are normally 0.001 and 1 pM, respectively. When perfused through the isolated gill, Small Cardioactive Peptide B (SCP B ) is found to suppress the gill withdrawal response amplitude with a threshold concentration of 0.01 pM and an EC 50 value of 0.03 nM. Suppression of the gill withdrawal response amplitude by Small Cardioactive Peptide B (SCP B )is found to be dose dependent and reversible up to a concentration of 1nM. At higher concentrations, the suppression tended to persist irreversibly. Small Cardioactive Peptide B (SCP B ) stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with an EC 50 of 0.1 and 1.0μM, respectively. |
| WGK Germany | 3 |
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现货供应
产品名: Small Cardioactive Peptide B SCPB 去供应商网站查看 询盘CAS: 84746-43-0
产地: 上海
规格: S877096
价格: 5mg-1996,1mg-666
库存: 15天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
现货供应
产品名: Small Cardioactive Peptide B SCPB 去供应商网站查看 询盘CAS: 84746-43-0
产地: 上海
规格: S877096
价格: 5mg-1996,1mg-666
库存: 15天内发货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2885703204/288570320
微信: 19863730987/17821173903
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